One of the biggest problems with animal experimentation is that animal-free methods enable research that would otherwise be impossible.

Animal experiments have a lot of limitations. But new technologies provide innovative ways to overcome these obstacles!

Here are some examples:

• Tissue on Organ-Chips can be observed via live imaging in real-time.¹
• Organ-Chips allow for tissue-specific non-invasive sampling during the observed processes.²
• Organ-Chips enable researchers to control every aspect of the microenvironment.³ They can also be used to compare the reactions of the same person to different treatments.⁴
• Gut-Chips allow for long-term anaerobic culture of human gut microbes (which is not possible in animals).⁵
• Brain-Chips can recreate reactions to chemotherapy for individual patients (decrease, resistance or aggressive growth of the same kind of tumour).⁶
• Placenta-Chips provide a highly controllable, dynamic microenvironment and permit the observation of cellular interactions and behaviour in real time.⁷
• The severity of the lack of oxygen can be adjusted and monitored in Organ-Chips (this plays a role in how cancer tissue reacts to treatment).⁸