| Rodents |
Humans |
| Plaque (fatty deposits) are deposited in the liver. |
Plaque is deposited in the blood vessels (leading to stroke and heart disease). |
| 3-year life span requires massive doses for drug/product testing - more than humans will ever use. |
72+ life span and consume drugs and chemicals in minute doses over a lifetime. |
| Imuran (immunosuppressive) causes birth defects in mice. |
Imuran does not cause birth defects in humans. |
| Manufacture Vitamin C in their bodies. |
Can only obtain Vitamin C through the diet. |
| Lysodren (cancer chemotherapy) does not cause kidney damage in rodents. |
Lysodren causes kidney damage in humans. |
| Continual pregnancy healthier for rodents. |
Continual pregnancy in humans leads to nutritional depletion and disease. |
| Hypersensitive to chlorine in minute doses. |
Can stand chlorine in much larger doses. |
| Manufacture Vitamin B in the appendix. |
Manufacture Vitamin B in the liver. |
| Myambutol (TB antibiotic) causes birth defects in mice. |
Myambutol does not cause birth defects in humans. |
| Eliminate drugs from the body in 3 hours (faster elimination reduces drug danger). |
Eliminate drugs in 72 hours. Increases danger of drugs in the aged. |
| Thymidine shrinks tumours in mice. |
Thymidine does not shrink tumours in humans. |
| Catapress (anti-hypertensive) causes retinal degeneration in rats. |
Catapress does not cause retinal degeneration in humans. |
| Can’t tolerate more than 15 minutes of direct sunlight. |
Can tolerate direct sunlight for much longer periods. |
| Chloroform toxic to mice in minute doses. |
Humans can stand Chloroform in much larger doses. |
| Obtain Vitamin D by licking their own fur. |
Obtain Vitamin D through the diet. |
| Moban (tranquilliser) causes breast tumours in mice. |
Moban does not cause breast tumours in humans. |
| Specially bred for laboratory studies. Live in a controlled sterile environment. Majority of diseases induced through genetic breeding (tumours and genetic defects), or from parasitic infections. |
Humans come from a wide variety of genetic, environmental and lifestyle backgrounds, all unpredictable. Environment, diet and lifestyles responsible for most human diseases. |
| Rats have no gall bladder - digest fats differently. |
Humans have a gall bladder. Digest fats differently. |
| Require 3 ½ times more protein than humans. |
Excess protein responsible for kidney damage in humans. |
| Thalidomide (tranquilliser) does not cause birth defects in rats. |
Thalidomide causes birth defects in humans. |
| Meclazine (for travel sickness) causes birth defects in rats. |
Meclazine does not cause birth defects in humans |
| Coumarin (blood thinner) causes liver damage in rodents. |
Coumarin does not cause liver damage in humans. |
