Cats are the most popular companion animal in New Zealand, with 41% of households sharing their home with at least one cat.1 The love and connection we have with these animals are reflected in the comparatively low number of cats used in research, testing and teaching and how they are used.

Many studies involving cats aim to improve their health and comfort in our homes, like surveying their humans to find risk factors for cats becoming overweight.2 However, some cats are still harmed for science; for example, wild cats are used in harmful ways for research aimed at trying to protect native wildlife.

Note: Cats living in the wild are often referred to as feral cats, but we will refer to these animals as wild cats.

Cats have been used in research, testing and teaching in various ways - from non-harmful to cruel and invasive methods. Most cats used for research, testing and teaching purposes are used for basic biological and veterinary research. They are also used in teaching, environmental management and more.

Cats in NZ have been used for:
  • Testing pet food formulations.
  • Veterinary research, including testing medications for feline diseases, studying disease symptoms and ways of diagnosis (like FIV, tooth decay, and cancer) and researching cat behaviour and health.
  • Environmental management, including testing toxic bait and traps, studying wild cat behaviour, optimising management methods (like killing trapped cats) and training staff to handle wild cats.
  • Teaching veterinary and vet nurse students basic concepts like animal handling and basic clinical/husbandry skills.

Places that use cats for science in NZ include private companies, universities, and polytechnics.

Cats used for science in NZ are sourced from breeding units, the wild (captured) and other public sources.*

*According to the Ministry for Primary Industries, public sources include: Public donations, animals obtained from a pound, a pet shop or other public sources. This includes companion animals who are used for the duration of the exercise (e.g. veterinary nurse training).

Discover real-life examples of how cats have been used in NZ below!

Measuring thickness of blood vessel walls

Colony cats were anaesthetised, and the blood vessels under their tongue were measured with a special hand-held camera.

Publication Link

Collecting faeces for lab tests

Colony cats were fed different diets for three weeks before their faeces was collected for analyses.

Publication Link

Surveying caregivers on their cat feeding

New Zealand cat caregivers filled in an online survey about their household demographics and what/how they feed their cats.

Publication Link

Testing new toxin in Hawke’s Bay (again)

Toxic bait traps were placed on a property in Hawke’s Bay. Cat population changes were monitored with stationary cameras.

Publication Link

Assessing stress reaction to anaesthesia in cats

Cats were put through several anaesthetic infusions with six-day breaks in between. Regular saliva samples were taken 24 hours before and after, and urine was collected through a wire mesh tray.

Publication Link

Trialling ready-made toxic bait

Toxic bait stations are set up in a regular pattern in an area and left for two weeks. Trial cameras and tracking tunnels monitor the effect on the population.

Publication Link

Studying medical data of cat and dog CT-imaging

Medical data from cats and dogs were gathered, and animals that had been euthanised for other reasons were examined.

Publication Link

Testing if a human diabetes drug might also work in cats

Research cats were placed in individual cages four times (one week each time) and injected with either a diabetes drug or a control solution. Several blood and urine samples were taken.

Publication Link

Testing a cat food supplement for tooth health

Colony cats were anaesthetised, and all plaque was removed from their teeth. Four weeks later, new plaque build-up was measured.

Publication Link

Sampling cats for feline immunodeficiency virus (FIV)

Buccal swabs (inside the cheek) were collected from almost 200 cats at 15 veterinary clinics.

Publication Link

Testing food preferences of cats

Cats were fasted for two hours in the mornings and then presented with different foods (lamb and beef parts) to measure their consumption.

Publication Link

Monitoring wild cats for a year

Wild cats are trapped and fitted with GPS collars. After one year, they are recaptured and killed.

Publication Link

Trialling a lighter rifle to kill trapped wild cats

Captured wild cats were shot in the head using an air rifle and were assessed to confirm death by recording the time to loss of heartbeat.

Publication Link

Testing a predictive marker for cancer survival in cats

Veterinary samples of cats with this form of cancer were analysed and compared with their remaining survival since diagnosis.

Publication Link

Monitoring outdoor cat behaviour

Privately owned cats with outdoor access were fitted with camera and GPS collars for up to three days.

Publication Link

Testing a diagnostic for feline coronavirus

Cats with specific symptoms were used to take blood, tissue, and fluid samples. Some blood samples were taken from control cats.

Publication Link

Studying the genes for hairyness

The hairiness of male and female cattle was rated. Some animals had their rectal temperature taken repeatedly, and some were shut in a hot room for two hours to make them sweat. Eight calves were killed to take brain samples.

Publication Link

Optimising fertility treatment

Young female cattle were treated with different hormonal injections to control their fertility cycle. Around ten rectal ultrasounds were done on each of them within 11 days, and several blood samples were taken in the next month. All but nine were artificially inseminated. The nine animals showed no fertility signs and were therefore useless for the study and the industry.

Publication Link

Trying out a health test for breeding bulls

Breeding bulls were infected with a skin fungus that usually results in a dangerous build-up in the gall and eczema. Through a special diet, bulls can be tested for their reactions via repeated blood samples and ranked for their genetic quality.

Publication Link

Testing a vaccine against miscarriage

Younger and older pregnant cattle were injected with a new vaccine against a parasite or just control solution. Skin reactions to the injection were checked, and blood samples were taken. Farmers reported miscarriages when they happened, and dead foetuses were collected if possible. If female calves were born, blood samples were taken from them, too.

Publication Link

Studying Johne’s disease

Some female calves of a group were infected with bacteria causing life-threatening sickness. Poo samples were collected directly from the rectum of all calves every other month. Half were killed to be dissected at 7 months, the rest at 15 months.

Publication Link

Studying Johne’s disease bacteria

Blood samples were taken from sick dairy cows who were sent to slaughter to see if their immune system was even putting up a fight. After slaughter, organ samples were taken.

Publication Link

Finding a gene to increase casein in milk

Breeding bulls were evaluated on their quality by judging, breeding, and milking their daughters. No exact numbers are stated how many lived to the end of the study (5 lactations).

Publication Link

Testing a new way to treat liver flukes

Young cattle were infected with liver flukes. They were treated with different medications or left untreated. Regular blood samples were taken from all animals for three weeks, and they were killed ten weeks later.

Publication Link

Studying effects of stunning before slaughter

Calves and sheep were anaesthetised. Some got 70-volt shocks to the shoulder. Others had a nerve exposed and stimulated before being stunned or cutting their throat.

Publication Link

Measuring brain reactions to stunning after killing

Calves were fasted for 24 hours and then anaesthetised. They were killed by their throats being cut, followed by stunning while measuring EEG/ECG (electronic heart and brain activity) and blood pressure.

Publication Link

Measuring brain reactions to stunning

Calves were fasted, anaesthetised and stunned with a non-penetrative bolt while being monitored for their response. After measurements were taken, they were killed.

Publication Link

Studying brain reactions to cutting blood vessels or neck tissue

Calves were anaesthetised, and their throat blood vessels exposed. While monitoring the brain“s activity (EEG) and blood pressure, either only the blood vessels or only the neck tissue was cut. The latter animals were then killed, too.

Publication Link

Measuring if being slaughtered is unpleasant

Calves were fasted, anaesthetised, and killed by cutting their throat. EEG and ECG (recording electronic heart and brain activity) were measured with electrodes in the head.

Publication Link

Measuring brain reactions to pain

Twenty calves were fasted and anaesthetised. Their horn buds were removed with a scoop, and pain response of the heart and brain with and without pain blockers.

Publication Link

Testing mastitis treatments

Dairy cows with an udder infection were treated with different antibiotic injections. Milk samples were taken to monitor results.

Publication Link

Trying to clone cows with more valuable milk protein

The genetic material of a cow foetus was manipulated and cloned into several cows. When they were less than one year old, they were injected with hormones to produce milk for sampling.

Publication Link

Analysing Greyhound race injury statistics

Historical data on Greyhound races between 2014 and 2019 were analysed. Injuries and deaths were investigated.

Publication Link

Using bones of euthanised shelter dog

Cadavers of dogs killed at an animal shelter were donated. Holes were drilled into leg bones and fitted with screws.

Publication Link

Investigating farm dogs for four years

Working farms dogs were examined regularly for four years. Health problems and fate were recorded.

Publication Link

Transplanting faeces as diarrhoea treatment

A dog with diarrhoea was treated with laxatives and warm water before a faeces sample from a healthy dog was inserted into his colon. Samples were taken before and after.

Publication Link

Testing the eyes of working dogs

Eye examinations were performed on working sheep dogs. Medication for pupil dilation was given, and faeces samples were taken from most dogs.

Publication Link

Analysing dog movements

Colony dogs were prepared with reflective markers and an activity collar. Their movements on a treadmill at various speeds were recorded.

Publication Link

Testing the effect of diet on farm dog performance

Working dogs were fed a diet very high or very low in carbohydrates. Their blood glucose and activity were monitored three times over four days each.

Publication Link

Testing a parasite treatment

After a pilot study with just one dog, six more were given an experimental parasitic treatment. Regular blood samples were taken through a catheter.

Publication Link

Teaching dogs to smell out catfish

Five pet dogs were trained over several months to identify catfish and goldfish smell in water samples.

Publication Link

Testing different combinations of pain meds

Eight dogs are treated with four different combinations of the test drugs in random order with two-week breaks in between. Two catheters are placed in leg veins (for drug injection and blood samples). For the test, dogs are fasted for 12 hours and anaesthetised. EEG is recorded with electrodes near the brain to measure response to electric shocks. Regular blood samples are taken for 8 hours.

Publication Link

Studying medical data of cat and dog CT-imaging

Medical data from cats and dogs were gathered, and animals that had been euthanised for other reasons were examined.

Publication Link

Teaching dogs to smell out koi carps (2019)

Three pet dogs were trained over several months to identify koi carb smell in water samples.

Publication Link

Testing working dogs for internal parasites

Faeces and blood samples were taken from working farm dogs.

Publication Link

Testing fluid management of dogs during anaesthesia

Dogs were anaesthetised. Their heart activity was measured while hey were injected with calculated amounts of fluid.

Publication Link

Trying to make rat poison unattractive for dogs

Dogs were fasted overnight and then given two food bowls with different kinds of repellent on one of them.

Publication Link

Surveying respiratory disease in racing Greyhounds

Laboratories sent in serum samples of dogs for analysis. Additionally, 17 racing Greyhounds were tested.

Publication Link

Studying fish behaviour in groups of multiple species

Mixed-species groups of fish (partly caught in the wild) were placed in a tank and fasted for 24 hours. Food was given and an artificial predator was used to study behaviour.

Publication Link

Studying food chains near CO2 vents

Fish and snails were observed and counted near CO2 vents and at control sites. Fish were also caught to examine their stomach content.

Publication Link

Studying fish behaviour in single-species groups

Young fish were caught in the wild and split into groups of 15, 75, and 150 animals. After being fasted for 24 hours, food was given and an artificial predator was used to study behaviour.

Publication Link

Testing the side-bias of fish (if they prefer to swim left or right)

Wild-caught fish were kept for 1.5 years before each fish was placed on a runway to observe their behaviour. Afterwards, fish were observed for schooling movements and some were killed to dissect their brains.

Publication Link

Studying effects of Climate Change on farming in damselfish

Fish were observed for their algae farming behaviour near CO2 vents and at control sites (Bay of Plenty). Small areas were covered to keep the fish away for a month and compare algae growths measured to compare.

Publication Link

Trying to estimate habitat quality from body condition

Snappers were hatched from eggs and raised on commercial food. They were kept in 800-litre flow-through tanks containing 170 to 260 fish each. At 80 days, they were fasted killed.

Publication Link

Trying different techniques for tagging fish

Fish were bait-trapped and treated for parasites. They were used to test different tagging methods. In the second part of the experiment, fish were caught with two different methods, after which injuries and survival over 12 days were monitored.

Publication Link

Studying fish near volcanic vents to learn about Climate Change

Fish near volcanic CO2 vents and at control sites were observed and counted. The reaction to baited underwater cameras and predator threats was filmed. Aquarium experiments were conducted with caught fish of different species.

Publication Link

Verifying “fish-friendly” flood pumps

Eels were caught, measured and tagged with transponders into the gut skin. They were later re-captured, observed for wounds and fungus and killed to examine internal damage.

Publication Link

Testing the temperature tolerance of Antarctic fish

Wild-caught fish were kept individually for months in tanks. During temperature experiments, fish of each group were tested for their breathing ability in small tubes before all fish were killed.

Publication Link

Slowly poisoning fish

Snappers were fasted for three days and then fed with toxic fish. Several died during feeding, and the rest were killed at the end.

Publication Link

Studying population changes in reef fish

Over 1,000 fish were caught by spearing at three NZ locations.

Publication Link

Testing the hearing of fish

Fish were anaesthetised and strapped to a plastic slide near an underwater speaker. Electrodes were placed in their head and gills to measure brain activity. For medical imaging, fish were restrained in a plastic tube with a sponge to keep them wet.

Publication Link

Developing a model for thermal stress in humans

Guinea pig pups were lightly anaesthetised, connected to devices measuring heart activity and breathing, and wrapped in a temperature-controlling blanket. Their body temperature was either forcefully raised or dropped.

Publication Link

Testing how too much fructose is bad during pregnancy

Female guinea pigs were mated; some were fed additional sugary water until birth. The pups were used for several glucose tolerance tests and X-rays. All pups were killed in the end.

Publication Link

Testing a seizure medicine for preterm babies

Pregnant guinea pigs were induced to give birth early, to test medication on their pups.

Publication Link

Testing the effects of sedatives

Young guinea pigs were treated with different sedatives. Their heart rate and blood pressure were measured before and during each treatment.

Publication Link

Testing an refined way of anaesthesia in guinea pigs

Guinea pigs were made to inhale anaesthetic gases. Different probes were inserted and attached to the animals to measure responses.

Publication Link

Studying the effect of fructose during pregnancy

Guinea pigs were fed either normally or supplemented with fruit sugar before and during pregnancy until birth. Mothers and pups were tested for glucose tolerance.

Publication Link

Studying the effects of meth

Guinea pigs were injected with sedatives, caffeine, and later meth. Under anaesthesia, their livers were cut out before they were killed.

Publication Link

Studying preterm birth effects on the brain

Pregnant guinea pigs were grouped to give birth normally or be induced early. The pups were put through behavioural tests and then killed for dissection.

Publication Link

Studying trauma and treatment of cochlear implants

After destroying their hearing with noise, guinea pigs were fitted with cochlear implants. Treatment success was tested before they were killed.

Publication Link

Testing the measurement of pupil reflexes in Alzheimer’s research

Guinea pigs were repeatedly flashed in the eyes with a phone light to record the pupil responses.

Publication Link

Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

Publication Link

Investigating mechanisms slowing down the heart rate

Young guinea pigs were injected with blood thinner before being anaesthetised and dissected.

Publication Link

Testing a device to assess hearing

Young guinea pigs were anaesthetised, electrodes placed under their skin, and their brain's response to sound was measured. All guinea pigs had one ear damaged, some both ears, before all were killed.

Publication Link

Studying changes in the inner ear due to inflammation

Guinea pigs were injected into the ear with bacteria. Medical scans were done after injecting chemicals, and most were killed for dissection.

Publication Link

Studying the effects of medication on memory

Guinea pigs were force-fed different drugs and later tested in a water maze before some were killed. Another group was exposed to carbon dioxide and decapitated.

Publication Link

Studying how anaesthetics affect intestine movement

Guinea pigs and rats were anaesthetised, then dissected, and then killed, in that order.

Publication Link

Researching scoliosis genes

Transgenic mice with a specific gene defect were mated. Pregnant mice were at several time points. The unborn babies were taken, skinned, and gutted to stain their skeletons for better pictures.

Publication Link

Studying hormone influences on obesity and fertility

Transgenic mice were bred to have diabetes symptoms. Together with control mice, they were fed a normal or a high caloric diet and compared for their fertility over 150 days.

Publication Link

Testing a new stroke treatment

Mice were squeezed into plastic cones, and test drugs were dripped on their nose. An artificial stroke was caused by injecting a chemical into their brain. Before and after, mice had to perform behavioural tests. All were then killed to take their brains.

Publication Link

Testing another new stroke treatment

Mice were operated on several times. They were made to experience an artificial stroke, were later injected with a possible treatment, and then were injected with a marker. The mice had their memory tested before they were killed.

Publication Link

Testing prostate cancer drugs

Mice were anaesthetised, and their prostate was injected with cancer cells or a control solution. A 42-day treatment course started three weeks later with different treatment drugs and control solutions. In the end, all mice were killed.

Publication Link

Testing a heart attack treatment

Mice were trained to eat jelly and then subjected to an artificial heart attack. They received either a new drug or a control substance. Regular heart ultrasounds were performed before they were killed and dissected.

Publication Link

Studying ovary problems caused by testosterone

Transgenic mice were implanted with a capsule containing either hormones or not. Vaginal smears were done for several weeks, and serial blood tests were performed twice. In the end, all mice were killed.

Publication Link

Testing an Autism treatment on transgenic mice

Mice were genetically modified to show "autism-like" symptoms. Together with control animals, they were either fed normally or with a high-zinc diet. Invasive behavioural tests were performed. At least some, likely all, were killed.

Publication Link

Comparing transgenic mice and humans

Mice were anaesthetised, and their body composition was measured several times. Their grip strength and balance were tested with lab equipment. In the end, all mice were killed.

Publication Link

Testing a new stroke drug for better dexterity

Transgenic mice were anaesthetised, and an artificial stroke was caused. They then received either a test drug or a control solution. After recovery, their food was limited to test their fine motor skills every other week. After two months, they were killed.

Publication Link

Testing migraine drugs

Mice were injected with potential migraine drugs and anaesthetised. Ultrasound imaging of their ears was taken. One ear was rubbed with capsaicin to record the increased blood flow and compare different drugs, doses, and time points.

Publication Link

Killing rats and mice for tissue

Rats and mice were anaesthetised, and their necks were broken. Their tissue was then used for research.

Publication Link

Studying Alzheimer’s and stroke symptoms

One group of transgenic mice were bred and killed at either four or 12 months of age by flushing their hearts. Another group was anaesthetised and caused to have a stroke. They were killed the same way.

Publication Link

Testing Alzheimer’s treatment on mice

Transgenic and “normal” mice were injected with a special protein and a chemical to mark new brain cells that may have been produced.

Publication Link

Testing a new Alzheimer’s drug

Newborn mice were killed to collect brain tissue. Adult mice were used to test drug reactions. They were anaesthetised twice; to inject the drugs and to flush their hearts and take their brains.

Publication Link

Testing if anaesthesia affects the sleep–wake cycle when combined with light treatment

Mice were kept on a 12-hour light/dark cycle and then switched to total darkness. During this time, they were exposed to light once, either with or without anaesthesia. The effect on their activity cycles was monitored. In the end, all were killed.

Publication Link

Studying the digestion of kiwifruit

Pigs were surgically fitted with an outside access to their intestine. Faeces were collected through anal stimulation, and samples were taken from the intestine for six-hour periods.

Publication Link

Testing feed supplements for their performance

Pigs were fed diets with different organic acids added. At a specific weight, they were slaughtered to collect samples.

Publication Link

Comparing the digestion of egg white in different forms

Pigs were acclimated to eating egg whites of different textures. After being deprived of water for two hours, they were fed again and then killed in intervals over six hours.

Publication Link

Testing ways of injecting nicotine

Pigs were anaesthetised and injected with nicotine through different methods. Blood samples were taken for two hours before the pigs were killed.

Publication Link

Measuring brain response to tail-docking

Piglets were bought at one to fifteen days old and anaesthetised. Their tails were cut off while measuring brain activity, and then they were killed.

Publication Link

Testing how cooking affects beef digestion

Pigs were fed ground beef for three days, either raw or cooked. They were then killed to cut out a part of their intestine.

Publication Link

Trialling a method to measure intestine fermentation

Young pigs were fed a test diet for two weeks while confined in metabolic chambers. After that, they were killed with an anaesthetic injected into the heart.

Publication Link

Testing how to gas piglets

Piglets were gassed plastic box to record their behaviour and vital signs.

Publication Link

Testing the accuracy of heart activity measurements

Pigs were anaesthetised, their open chests were equipped with electrodes and closed again. After measurements, the hearts were stopped, images were taken, and the hearts were removed.

Publication Link

Testing cholesterol absorption from baby formula

One-week-old piglets were kept in metabolic crates and fed baby formula for three weeks. They were then anaesthetised and killed to be dissected.

Publication Link

Studying the digestion of protein through serial slaughter

Ninety young pigs were housed individually for 13 days; their diet contained kiwi fruit and beef. All were killed to be dissected.

Publication Link

Studying the inner functions of the heart

Pigs were anaesthetised and their chests were cut open. Electrodes were inserted into their hearts so measurements could be taken before their hearts were removed.

Publication Link

Testing the effect of pain killers during tail docking

Piglets were anaesthetised and their tails were removed using different methods. During these procedures, the heart and brain activity of the pigs were measured.

Publication Link

Testing if pigs spread kauri tree sickness

A group of pigs was fed infected kauri roots for one day, and their faeces were collected for a week. Over 270 wild pigs were shot, and their stomach contents was sampled.

Publication Link

Trialing xenotransplantation for diabetes

Four pigs were used to harvest cells for transplantation into humans.

Publication Link

Studying sow and piglet behaviour in crates and pens

Sows and their newborn piglets were put in tightly confined crates or pens with slightly more room and their behaviour was observed.

Publication Link

Studying food intake in an autism "model"

Pregnant rats were injected to cause autism-like symptoms in their babies. The male babies were put through behavioural tests with control animals as well as a feeding study. Some were fasted for 16 hours and killed by flushing their hearts.

Publication Link

Testing the safety of a probiotic supplement

Rats were force-fed with a probiotic solution or control solution. After two weeks, they were killed for dissection.

Publication Link

Studying the effects of obesity and mussel powder on bone health

Rats were kept alone and fed different diets containing normal or high amounts of fat or sugar. Some were supplemented with Greenshell mussel powder. X-rays were done, and some rats' ovaries were removed. Ultimately, all were killed by bleeding them out.

Publication Link

Testing if a brain region controls memory

Some rats had their brains surgically heat-damaged. Electrodes were implanted to monitor brain activity and to stimulate the damaged parts with light. Rats then had to re-perform memory tests to see the impact before all were killed.

Publication Link

Studying the communication between inner ear and brain

Rats were anaesthetised, and their inner ear was partly removed, before parts of their brains were stimulated with wire electrodes. Reactions of the rat's eyes and brain were recorded. In the end, all rats were killed.

Publication Link

Testing a connection between tinnitus and brain function

Rats were anaesthetised and one ear was damaged with noise. Rats were taught that silence meant they would get electric shocks and freeze in fear. This was a test for tinnitus.

Publication Link

Testing diabetic rats’ hearts

Genetically diabetic fat rats and their lean littermates were anaesthetised. Ultrasound images were made from their hearts. All were killed and dissected.

Publication Link

Testing the effect of diabetes on pregnancy hormones

Rats were anaesthetised, and their brain was accessed through the mouth to measure reactions to stimulation. In the end, all rats were killed.

Publication Link

Trying to study schizophrenia

Half of a group of pregnant rats were injected to affect their babies' brain development. Some pups were allowed to grow up to test their behaviour.

Publication Link

Releasing a rat family into the wild to see where they go

A wild-caught rat was mated, fed a fluorescent dye, and released again with her pups. Traps, tunnels, and cameras were set up to track and eventually recapture the animals, which did not work 100%.

Publication Link

Comparing digestion of sheep versus cow milk yoghurt

Rats were fed cow milk, sheep milk, cow yoghurt or sheep yoghurt for two weeks. They were gassed with CO2 before their necks were broken.

Publication Link

Testing a rat poison that is unattractive for dogs

Rats were kept in small cages and fasted overnight. Then, they were given two food trays. One of them was scented with lion, tiger, or dog faeces.

Publication Link

Comparing digestion of sheep versus cow milk

Rats were fed a test diet containing beef protein and received cow milk or sheep milk instead of drinking water. After 28 days, all were killed.

Publication Link

Testing medication after heart attack

Rats were anaesthetised, and their hearts were exposed. A heart attack was simulated by blocking an artery. Some had dye injected into their brains, and some were injected with test drugs. All animals were killed.

Publication Link

Testing a medicine against drug addiction

Mice's tails were dunked in hot water. Rats were put through cycles of drug-seeking and withdrawal using self-injection of cocaine. Other rats were injected, and their behaviour was tested (with the notorious Forces Swim Test, among others).

Publication Link

Studying cell death in breast tissue

Mother rats had some of their newborns taken away, and several of her teats were sealed off after two weeks. They were killed after different waiting times to analyse the dying tissue.

Publication Link

Investigating how worms spread between lambs and calves

Lambs and calves were infected with worm eggs to see if parasites from cattle can infect sheep.

Publication Link

Using sheep to try and model how well humans will heal after dental surgery

Sheep had healthy teeth pulled out and the sockets treated in different ways to compare how well the body will heal after a tooth is removed when left untreated vs using a bone graft.

Publication Link

Preclinical testing of a gene therapy for Batten disease

Sheep with and without a specific gene mutation were checked and scanned regularly for nine months. Affected sheep received gene therapy at different ages. Treated sheep were killed.

Publication Link

Testing if blocking a cell signal can prevent foetal brain injury

Pregnant sheep were anaesthetised, and the foetuses fitted with electrodes. The umbilical cord was blocked for most of them, and half were treated with a test drug. Mothers and unborn lambs were killed three weeks later.

Publication Link

Testing the combination of drugs for congestive heart failure treatment

Sheep were anaesthetised and subjected to surgery. Electrodes were used to pace their hearts faster while testing the effect of different drugs.

Publication Link

Testing the best way to deliver gene therapy drugs

Sheep were anaesthetised. Their heads were drilled into, and their brains injected with test drugs. They were killed after three weeks.

Publication Link

Testing the potency of pneumonia vaccines for sheep

Lambs were vaccinated twice and regular blood samples were taken for 34 weeks, to test different pneumonia vaccines for sheep.

Publication Link

Testing the effects and wash-out of painkillers

Lambs were treated with different painkillers or no painkillers at all before tail docking and castration. Their behaviour was monitored.

Publication Link

Developing “hyperimmune” milk

Sheep were injected with Covid-19 vaccines to see if they produced milk that could be marketed to consumers as providing immunity against certain diseases.

Publication Link

Studying the genetics of Batten disease on chimeric lambs

Sheep foetuses were removed. After swapping cells between them, they were inserted into other ewes. Lambs born were subjected to X-rays and, at one to three years old, were bled out for dissection.

Publication Link

Testing pacemaker adjustments

After causing them heart failure, sheep were surgically fitted with pacemakers and measurement devices. Those who survived the procedures were killed after six months.

Publication Link

Studying methane emission and meat quality

Lambs were tested and killed to assess the relationship between methane emissions, carcass weight and meat quality. Almost 2,000 were put through emission measurements. Over 17,000 were slaughtered.

Publication Link

Studying the effect of chemicals in normal and high blood pressure

Sheep were surgically fitted with a clip around an artery and compared with others without clips. Measuring devices were added before injecting different chemicals into the hearts of the conscious sheep.

Publication Link

Comparing success of muscle repair surgery with or without weeks of delay

Sheep were anaesthetised and one side of a pelvis muscle was detached. After several weeks, the muscle was repaired. How well the sheep then walked was noted before all were killed.

Publication Link

Comparing different designs of dental implants

Sheep were anaesthetised. One leg bone was exposed and fitted with several implants. After 12 weeks, all were killed.

Publication Link

Trying to model human brain injuries

To study changes in different areas of the brain after brain injuries. Sheep were used to study the effects of traumatic brain injuries in humans.

Publication Link

Investigating intestine movements

Young pigs and NZ White rabbits were anaesthetised. A part of their intestine was pulled out far enough to record its movements and signalling.

Publication Link

Harvesting rabbit and pig eyes for lab tests

The eyes of slaughtered rabbits and pigs killed for experiments were used to analyse the structure of the cornea.

Publication Link

Causing sinusitis in rabbits as a model

NZ White rabbits were anaesthetised, and a sinus tract in their nose was blocked for four weeks to cause sinusitis. After another ten weeks with regular samples, they were killed.

Publication Link

Testing a new vaccine

NZ White rabbits were injected with a new vaccine type several times before being killed.

Publication Link

Harvesting eyes for lab tests

The eyes of pigs and rabbits killed for experiments were used to analyse the structure of the cornea.

Publication Link

Testing the toxicity of some substances

Young NZ White rabbits were force-fed different doses of toxic substances. Blood samples were taken before and immediately after killing them at set time points (or to end their suffering).

Publication Link

Using a new imaging technology

One NZ White rabbit and rats were killed, and their eyes were removed to use for the study.

Publication Link

Measuring contractions in exposed rabbit uteruses

Pregnant rabbits were anaesthetised, and their uterus was exposed. Measurements were taken while contraction-inducing injections were given. Then they were all killed for dissection.

Publication Link

Mapping wave patterns of the small intestine

NZ White rabbits were anaesthetised, their intestines were used for electrode mapping, and then they were killed.

Publication Link

Studying presence of a virus in rabbits

Wild rabbits were shot, caught by dogs or trapped to test them for virus strains. The infectious solution was then fed to NZ White rabbits in a lab to kill them later.

Publication Link

Harvesting rabbit colons for lab tests

NZ White rabbits were anaesthetised, a part of their intestine was cut out, and then they were killed.

Publication Link

Harvesting rabbit bladders for lab tests

NZ White rabbits were anaesthetised, their bladder was cut out, and then they were killed.

Publication Link

Testing an antimicrobial eye medication

NZ White rabbits were treated with Manuka honey solution in one eye and a control solution in the other eye for five days. Different values like tearing and irritation were measured.

Publication Link

Using muscles of dead rabbits for imaging

Two NZ White rabbits were killed to use for detailed muscle imaging.

Publication Link

Measuring jaw bone growth in young rabbits

Young rabbits were anaesthetised and had holes drilled into their jawbones to implant small pieces of metal. X-ray scans were made, and the rabbits were killed.

Publication Link

Testing the welfare impact of pindone toxin

Three groups of young NZ White Rabbits received pindone-toxin pellets on different schedules. Any rabbit still alive after three weeks was killed.

Publication Link

With your help we can end animal experimentation in Aotearoa.