Cattle

Cattle are one of the most used animals for science in NZ. Learn about the many ways they are used!

Thousands of cattle are used for scientific purposes in Aotearoa every year. In fact, they have been one of the most commonly used animals in NZ science since 1989!

This sadly makes sense when you consider how widely they are exploited for their milk and their bodies.

The species of cattle is simplified to cows by many people. Actually, only the mothers are called cows:

  • Heifers are female cattle before they become mothers.
  • Calves are their babies.
  • The males are referred to as bulls (or steers if castrated).
Animal agriculture:

Thousands of cattle are used in Aotearoa every year in research aimed at trying to sustain, enhance and make more money for the animal agriculture industry.

Examples include research into:

1. Decreasing their negative impact on the environment - a cow on its own won't create a huge impact but because we have bred so many cattle in NZ, their collective impact is huge!

  • Cattle have been put in respiration chambers so the amount of methane they produce can be measured. Researchers have also glued urine sensors around their vulva to try and investigate ways of reducing the amount of nitrogen produced in their urine (methane and nitrogen can create negative impacts on the environment).

2. Increasing the survival rate of calves - not for the calves themselves but so the animal agriculture industry doesn't lose as much money.

3. Learning more about the fertility of cows (i.e., trying to improve artificial insemination and reduce the rest time in-between pregnancies for cows). Again, this research is not done for the cows themselves but so they be made pregnant as often as possible so that more money can be made from their exploitation.

4. Genetic modification to try and create more desirable traits in cattle (i.e., genetically modifying cows to change the properties of their milk).

5. Diseases that cattle on farms often get such as lameness, mastitis (a common infection of the udder in dairy cows) and fungal and parasitic infections. This type of research often involves making the animals sick on purpose.

6. Ways of housing and keeping large numbers of cattle on farms (i.e., research into bedding, floor types, shelter, shade and hygiene practices).

7. Trying to find more “humane” slaughter methods (i.e., investigating what type of gas kills piglets the quickest and if stunning animals before killing them creates less of a pain response).

8. Different types of pain relief for standard procedures in the animal agriculture industry (i.e. dehorning, castration, C-section).

9. Safety tests for chemicals and animal remedies, including medications, supplements and fertilizers.

10. Increasing milk or muscle (beef) production (i.e., feeding cattle different additives and measuring how its digested).

Fistulation: Cattle with holes cut into their bodies

For decades, researchers have artificially created fistulas (also known as cannulas) in ruminant animals such as cattle, sheep and deer. These are essentially window-like holes in the side of an animal's body.

Fistulas are tubes that are created surgically to connect a cow or sheep’s stomach to her skin. The outside of the fistula is covered with a plastic cap that can be opened by scientists to remove stomach contents for analysis or introduce foreign substances.

It is a painful procedure and cows are still suffering from the intrusive surgery up to 11 days after the surgery. Learn more here.

Additional calf exploitation - the calf blood industry

Calves and calf foetuses are killed, and the blood is drained from their bodies to be used in other research.

There are two main types of calf blood products: Fetal bovine serum and New Born Calf Serum.

Fetal bovine serum is taken from foetuses that have been removed from their mothers in slaughterhouses after they have been killed. A needle is injected into the foetus’ heart, and the blood is pumped out. The foetuses have to be alive during this so that their blood comes out easier. They also have to be at least three months into the gestation period to ensure that their heart is large enough to puncture.

Newborn Calf Serum is sourced similarly; calves who are 20 days old or younger have their heart punctured and are bled to death.

These products are used as a media base and growth supplement in many different types of research.

In the news

Mycoplasma Bovis: "Researchers will measure how M. Bovis impacts infected animals and herds, including physical signs, effects on milk yield and quality, weight gain in cattle, and the duration of these effects." Read more.

Cow shock collars: "Animals wear GPS-enabled collars that identify their location relative to invisible fence lines created on a digital farm map. The animals are trained to be guided by audio prompts (beeps) from the collars when required. As an animal gets close to a virtual fence, a series of beeps alerts them to the fence boundary. If they cross the fence line, they receive a "disincentive", a mild electric shock, and are guided back inside the line." Read more.

Bobby calves: Bobby calves (male calves of dairy cows) are normally unwanted by the dairy industry. Researchers are cross-breeding dairy cows with beef breeds so that bobby calves can be killed and eaten after a year, rather than being killed as "excess" after 4 days. Read more

Climate change: AgResearch scientists have been given $10 million to develop cattle better adapted to warmer temperatures and to lower methane emissions. Read more.

Places that use cattle for science in NZ include universities such as Lincoln University (who have their own research dairy farm) and Massey University (they also have their own dairy farms), private companies such as Abacus Bio Limited and Cognosco, crown institutes such as AgResearch, industry bodies such as Dairy NZ and by other organisations and individuals.

Cattle used for science in NZ are sourced from commercial establishments, farms, public sources, breeding units and other sources.

Discover real-life examples of how cattle have been used in NZ below!
References:

Testing a new papillomavirus vaccine

Adult colony cats were injected with a new vaccine or a control solution. Regular skin swabs and blood samples were taken.

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Testing the effect of dietary fibre in cat food

Cats received three diets for three weeks each. Food intake was measured daily, and urine and faeces were collected for the last 5 days each time.

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Determining how common E. coli is in pets

Rectal swaps were taken from cats and dogs presented at veterinary clinics, and their caregivers filled out a questionnaire.

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Tracking and killing wild cats

Wild-caught cats were used to train sedation and collar fitting before being killed. Another group of cats was fitted with GPS collars for one year before being tracked down and shot.

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Scoring the body condition of colony cats

The body condition score of 101 cats was determined, adding to routinely collected body weight data from the breeding colony.

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Testing new toxin at Ngatapa Station

Toxic bait traps were placed on a property in Hawke’s Bay. Cat population changes were monitored with stationary cameras.

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Testing a possum poison for other animals’ safety

Dogs, chickens and wild-caught cats were fed dead possum. Once they got used to eating this, they were fed possums killed with sodium nitrite, and signs for poisoning were monitored.

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Testing nutritional value of new pet food

Cats and dogs were fed a test diet exclusively for several months. Some adults are kept in metabolic chambers for 10 days, and blood samples are taken at the end.

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Testing new toxin at Toronui Station

Toxic bait traps were placed on a property in Hawke’s Bay. Cat population changes were monitored with stationary cameras.

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Surveying caregivers on their cats’ personality

Cat caregivers in Australia and New Zealand filled in an online survey about their cats’ personality traits.

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Training staff in wild cat handling

Wild cats are trapped and used to train staff in handling, sedation and collar fitting before they are killed.

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Sampling cats’ saliva for feline autoimmune disease

Buccal swabs (inside the cheek) were collected from all cats in three British Shorthair breeding catteries.

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Measuring vitamins in blood samples

Blood samples were taken from colony cats of different ages.

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Collecting blood plasma for tests

Colony cats are switched from wet food to dry food for two days. Blood samples are taken before and after.

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Testing a breathing mask on cats and dogs

Cats and dogs were held down tightly and fitted with face masks. Their breathing was measured for a while.

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Testing pain medication with lasers

Colony cats were put into small chambers, and a laser was pointed at a shaved skin patch. The influence of medication on their reaction time was measured.

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Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

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Testing a fertility treatment

Cows with fertility problems were treated with hormones for ten days or left untreated. All were then artificially inseminated.

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Testing a supplement for more calcium intake

Pregnant cows were fed with or without a specific feed additive. After birth, all were fed the same diet. Blood samples were taken in the weeks around birth.

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Checking endometritis rates in dairy herds

Some cows in several dairy herds were selected, and their vaginal discharge was measured and sampled. They were then impregnated as per standard agricultural practice.

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Comparing weight gain with different diets

Newborn calves were raised on various milk, pasture, and pellets combinations. They were slaughtered at two years old, and their “quality” was measured.

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Testing pain meds for disbudding

The horn buds of young calves who were slightly sedated were burned off with a hot iron. Half of them received pain meds beforehand, and blood samples were taken before and after. After 24 hours, the second group received pain meds, too.

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Studying Ikeda infection and treatment

Regular blood samples were taken from cows on three different farms. Only some were treated against the parasite. Milk production and fertility were recorded.

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Studying diarrhea infection

New mother cows had blood samples taken. If the sample was negative for a diarrhoea virus, they were sampled again after a while.

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Studying genes for body size

Udders of dairy cows were slightly cut with a scalpel, and a tissue sample was taken with a biopsy needle.

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Testing toxicity of a potential new fertiliser

Pigs were fed toxic bait and monitored until they died.

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Studying stress around birth

Blood samples were taken from cows with a high or low risk of health concerns after birth.

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Studying genetics of a missing tail

Cloned foetuses were implanted into female cattle to research taillessness. Some of them were killed during pregnancy to examine the foetuses. One tailless animal was killed at age 4, and one of the cloned calves died after birth.

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Studying Ikeda (parasite) infection

Blood samples were taken from dairy cows and their calves directly after birth before separating them. After four months, the calves were sampled again.

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Studying Osteoporosis in cows

Young female cattle who had given birth for the first time were sent to slaughter. Half of them had broken bones for between 2 and 10 days. Blood samples were taken before slaughter, and bones were collected after.

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Testing a tuberculosis vaccine

Male calves were infected with bacteria. Two groups were vaccinated before or after the infection, and the third group was left untreated. All were killed and dissected 13 weeks later.

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Testing feeding plans for better immunity after calving

Pregnant cows were fed either a bit too much or a bit too little. Blood samples were taken before, at, and after calving. Researchers also took liver samples with a 20-cm biopsy needle and vaginal samples with a small brush and a scoop at these dates, except for the date of birth.

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Analysing Greyhound race injury statistics

Historical data on Greyhound races between 2014 and 2019 were analysed. Injuries and deaths were investigated.

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Using bones of euthanised shelter dog

Cadavers of dogs killed at an animal shelter were donated. Holes were drilled into leg bones and fitted with screws.

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Investigating farm dogs for four years

Working farms dogs were examined regularly for four years. Health problems and fate were recorded.

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Transplanting faeces as diarrhoea treatment

A dog with diarrhoea was treated with laxatives and warm water before a faeces sample from a healthy dog was inserted into his colon. Samples were taken before and after.

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Testing the eyes of working dogs

Eye examinations were performed on working sheep dogs. Medication for pupil dilation was given, and faeces samples were taken from most dogs.

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Analysing dog movements

Colony dogs were prepared with reflective markers and an activity collar. Their movements on a treadmill at various speeds were recorded.

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Testing the effect of diet on farm dog performance

Working dogs were fed a diet very high or very low in carbohydrates. Their blood glucose and activity were monitored three times over four days each.

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Testing a parasite treatment

After a pilot study with just one dog, six more were given an experimental parasitic treatment. Regular blood samples were taken through a catheter.

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Teaching dogs to smell out catfish

Five pet dogs were trained over several months to identify catfish and goldfish smell in water samples.

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Testing different combinations of pain meds

Eight dogs are treated with four different combinations of the test drugs in random order with two-week breaks in between. Two catheters are placed in leg veins (for drug injection and blood samples). For the test, dogs are fasted for 12 hours and anaesthetised. EEG is recorded with electrodes near the brain to measure response to electric shocks. Regular blood samples are taken for 8 hours.

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Studying medical data of cat and dog CT-imaging

Medical data from cats and dogs were gathered, and animals that had been euthanised for other reasons were examined.

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Teaching dogs to smell out koi carps (2019)

Three pet dogs were trained over several months to identify koi carb smell in water samples.

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Testing working dogs for internal parasites

Faeces and blood samples were taken from working farm dogs.

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Testing fluid management of dogs during anaesthesia

Dogs were anaesthetised. Their heart activity was measured while hey were injected with calculated amounts of fluid.

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Trying to make rat poison unattractive for dogs

Dogs were fasted overnight and then given two food bowls with different kinds of repellent on one of them.

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Surveying respiratory disease in racing Greyhounds

Laboratories sent in serum samples of dogs for analysis. Additionally, 17 racing Greyhounds were tested.

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Studying how viruses spread in fish

Fish were caught with nets and killed.

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Using fish to study the impacts of Climate Change

Fish were either bought or caught and killed so that they could be dissected.

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Overfeeding Zebrafish to learn about obesity

Normal and transgenic zebrafish were fed normally or way too much. The fish were taken out of the water for glucose tests and blood samples.

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Studying gut bacteria in fish

Nine fish were caught by underwater spearing and killed so that samples could be collected from their digestion tracts.

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Studying the sleep of sharks

Sharks were caught and kept in outside tanks. For the experiments, they weren't fed for at least 4 days, of which they spent 3 days in a measuring chamber not much bigger than the shark. Oxygen consumption and behaviour were continuously recorded for the last 24 hours.

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Infecting fish larvae as a potential model for humans

Zebrafish larvae were injected with bacteria to test how their immune system responds. This was repeated to test how well the immune system reacted and how long the effect lasts.

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Finding a “growth gene” in snappers

Snappers were caught from the wild and bred. Around eighty-thousand of their offspring were hatched and raised. At regular “grading” events, injured and deformed fish were disposed of. At just under a year old, around twenty-two-thousand were left and transported to a sea pen, where they were raised to 17.5 months old before harvesting.

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Testing how much fat you can feed fish

Fish in aquaculture were divided into groups and fed diets with different fat content. Fish were anaesthetised and faeces samples squeezed out of them.

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Testing fish for mercury contamination

Wild fish were caught, measured and frozen to be analysed.

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Measuring how stress affects fish

Fish were exposed to chronic stress for four weeks, while 57 non-stressed animals were kept as a control. Signs of stress were noted. At the end of the experiment, all were chilled to death.

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Exposing fish to herbicides

Zebrafish were kept in tanks that were contaminated with different herbicide concentrations for 10 days. They were then mated to herbicide-exposed or control fish. Both generations were tested on behavioural changes at around 4 months of age. 24 fish per treatment were killed and dissected.

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Testing supplements as protection from toxins in over 1,000 fish embryos

Embryos were harvested and kept in Petri dishes for toxicity and treatment tests. Embryos were treated with an antioxidant, a gold salt or both on the first day, and abnormal development was measured on day 5.

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Studying effects of drying rivers on mudfish

Water depth and quality were measured at 24 different sites. Several traps for fish and invertebrates were set at 8 visits, sampling and mostly killing the caught animals (including 15 individuals of the endangered Kōwaro).

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Studying bacterial spread in fish larvae

Bacteria were genetically modified and made fluorescent. Zebrafish were bred, and their larvae were infected with the bacteria. The fish were killed for analyses or used for live imaging under a microscope (and then killed, most likely).

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Investigating effects of invasive fish removal

Using fyke nets and electrofishing, fish were caught on four occasions. Fish were marked with fin clippings around one big removal event where 3 tonnes of fish were caught. In recaptures a week after each marking event, invasive fish caught were killed after the examination.

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Studying fish life cycles

Fish were sedated and their blood and ovarian tissue were sampled three times.

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Questioning vets on pain management

Veterinarians completed a questionnaire regarding pain and pain management in rabbits and guinea pigs.

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Testing nerve reactions to electric stimulation

Young guinea pigs were bled to death. Specific nerves were removed and experimented on.

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Studying short-sightedness

Guinea pigs had one eye covered for two weeks before increasing their eye pressure surgically and kill them.

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Measuring nerve reactions to gases

Guinea pigs were anaesthetised, and their windpipe and blood vessels were cannulated. They were exposed to different gases and cyanide while measuring breathing and nerve activity.

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Studying how anaesthesia affects breathing and heart

Guinea pigs were put in airtight chambers to test the effects of low oxygen. Some were surgically fitted with tubing so blood samples could be taken during the tests. In the end, all were killed.

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Studying compensation after inner ear destruction

Guinea pigs were anaesthetised, and their inner ear was destroyed with a drill. Videos were made for over two days of their balance recovery.

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Killing pregnant guinea pigs for tissue cultures

Pregnant guinea pigs were anaesthetised at specific time points of their pregnancy, including during labour, to then remove the uterus for tissue culture experiments.

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Testing how oxytocin injections cause contractions

Pregnant guinea pigs were surgically implanted with electrodes on or near the uterus. They were injected with oxytocin in specific doses and timeframes, and the effects were measured.

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Harvesting testicles for studies

Male guinea pigs were killed with CO2 to remove their testicles for experiments.

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Testing a new tuberculosis vaccine

A new tuberculosis vaccine was tested by injecting guinea pigs with the bacteria, either with or without prior vaccination. After several weeks, all were killed.

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Testing how heart calcium metabolism is different in species

Guinea pigs and rats were decapitated, and their hearts were quickly removed to study them.

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Testing influences on the rate of a dissected heart

Albino guinea pigs were anaesthetised and dissected before they were killed.

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Confirming the correlation of energy storage and stress in the inner ear fluid

Guinea pigs were anaesthetised and artificially ventilated. Ear fluid samples were taken through a hole in the skull, while exposing them to noise or lack of oxygen.

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Comparing natural and genetically altered tuberculosis strains

Guinea pigs were infected with tuberculosis strains after being injected with bacterial proteins beforehand. In the end, all guinea pigs were killed and dissected.

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Comparing effects of anaesthetics on breathing and heart rate

Guinea pigs, rabbits and rats were anaesthetised, and a tube was put into their windpipe through the neck. They were made to breathe anaesthetic gas.

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Testing a UV treatment for bacterial eye infection

Pigs’ eyes were acquired for testing a new treatment, followed by tests on live mice, most of whom were killed.

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Studying methane emission and meat quality

Sheep were bred for high and low methane emissions. Almost 2,000 were put through emission measurements. Over 17,000 were slaughtered.

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Testing if anaesthesia affects the sleep–wake cycle

Mice were kept on a 12-hour light/dark cycle and then switched to total darkness. They were anaesthetised twice to see the effect on their activity cycles, and all were killed in the end.

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Testing the influences on growth

Transgenic and "normal" mice were kept in small groups and killed at different ages. Fat and muscle tissue were dissected, and the hearts were taken.

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Testing a new way to kill lab mice

Mice were fed cream cheese containing different amounts of a sedative. Behaviour was recorded during the sedation period and while gassing them with CO2.

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Testing a possible cause for cataracts

Transgenic and "normal" mice were used to study the development of cataracts. They were anaesthetised, images of their eyes were taken, and then they were (likely all) killed.

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Studying chronic stress

Mice were handled daily, had vaginal smears, and some were subject to the notorious Forced Swim Test. Half of them were additionally stressed daily in various ways to see the difference it makes.

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Trialling cancer drugs in mice after similar drug failed in humans

Mice were force-fed daily with two new drugs in different dosages. Others were force-fed a control solution, and some were left untreated. In the end, the animals were killed with CO2 and dissected.

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Testing if exercise influences treatment success with cancer

Mice were injected with cancer cells. When tumours reached an “ethical” limit, they were injected with a labelling agent, anaesthetised and killed to be dissected. This was repeated, while some mice received cancer treatment.

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Testing if exercise influences muscle mass with cancer

Mice were injected with cancer cells, and some received immunotherapy once the tumour reached a specific size. When tumours reached an “ethical” limit, they were killed. Cancer-free control mice were killed simultaneously.

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Studying the interaction of hormones and stress

Transgenic mice had their brains injected, some had their ovaries removed, and some were restrained for repeated blood samples. In the end, all mice were killed.

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Studying movement processing in the brain

Transgenic mice were put through behavioural tests while half of them had a part of their brain-damaged. Some mice had a window put into their skull to take recordings of their brains while awake. They had limited access to water and were forced into a device that stopped them from moving their head. In the end, all were killed.

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Testing seizure activity in transgenic mice

Mice with specific genetic limitations were bred. Some were killed for dissection, and others were injected with a gene activation drug before they were killed.

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Testing a seizure treatment

Genetically modified mice had wires and a cannula implanted in their brains, and were injected to cause seizures. The next day, their genetic mutation was activated. The test was repeated before they were all killed.

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Observing cancer growth with/without treatment

Mice were injected with human breast cancer cells. The growth was monitored and sampled (biopsy). Some were operated on to remove their ovaries and some were treated with drugs before all were killed.

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Testing how hormones influence activity while pregnant

Transgenic and “normal” mice were used to test the influence of pregnancy and hormones on activity and anxiety. They were kept in single cages with running wheels and subjected to behavioural tests. The transgenic mice were killed in the end.

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Harvesting colon tissue for laboratory tests

Pigs were killed and their colon tissue was used for laboratory testing.

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Testing if pigs can be fed by-products from biofuel and food processing

Pigs were fed a standard diet or a diet containing by-products from other industries. They were slaughtered to compare meat growth and quality.

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Studying starch digestion in pigs to try and model humans

Pigs were fed different diets containing durum wheat or rice. Some had regular blood samples taken through a catheter. All the animals were killed at the end.

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Validating a treatment for stomach muscle dysfunctions

Pigs were anaesthetised, their bellies were opened, and electrodes were placed on their stomach walls before and after damaging some stomach tissue with heat. All pigs were killed.

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Assessing pigs as digestion models for humans

Titanium tubes were implanted into pigs’ intestines. Digested food was collected through the tube for 9 hours.

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Testing the effect of different species’ milk on brain gene expression

Piglets were fed different kinds of milk from other species for 15 days. They were killed to dissect their brains.

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Testing transmitter implantation on wild pigs

Wild pigs were captured, and three different tracking devices were fixed to or implanted into each one. After 104 days, they were tracked down and killed.

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Investigating oxygen content in the gut

Pigs were fed diets with different or no protein sources as a control. After a week, all were killed.

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Testing a UV treatment for bacterial eye infection

Pigs’ eyes were acquired for testing a new treatment, followed by tests on live mice, most of whom were killed.

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Testing the effect of different species’ milk on protein digestion

Piglets were fed different kinds of milk from other species for 15 days. They were killed to dissect their stomachs.

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Testing the strain on a temporary surgical implant

A surgical implant was screwed to a severed pig head, and measurements were taken via laser scanning.

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Investigating intestine movements

Young pigs and NZ White rabbits were anaesthetised. A part of their intestine was pulled out far enough to record its movements and signalling.

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Harvesting rabbit and pig eyes for lab tests

The eyes of slaughtered rabbits and pigs killed for experiments were used to analyse the structure of the cornea.

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Harvesting eyes for lab tests

The eyes of pigs and rabbits killed for experiments were used to analyse the structure of the cornea.

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Testing a treatment for stomach muscle dysfunctions

Pigs were anaesthetised, their bellies were opened, and electrodes were placed on their stomach walls before and after damaging some stomach tissue with heat. All pigs were killed.

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Testing how electric stimulation affects stomach movements

Nine pigs were anaesthetised, their bellies were opened, and electrodes were placed on the stomach walls. Electric stimulation tests were performed before the pigs were killed.

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Comparing effects of anaesthetics on breathing and heart rate

Guinea pigs, rabbits and rats were anaesthetised, and a tube was put into their windpipe through the neck. They were made to breathe anaesthetic gas.

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Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

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Using sheep to try and model how well humans will heal after dental surgery

Sheep were anaesthetised, three teeth were pulled, and the sockets were treated differently. For months, regular samples were taken from the healing wounds before all sheep were killed.

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Preclinical testing of a gene therapy for Batten disease

Sheep with and without a specific gene mutation were checked and scanned regularly for nine months. Affected sheep received gene therapy at different ages. Treated sheep were killed.

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Testing if blocking a cell signal can prevent foetal brain injury

Pregnant sheep were anaesthetised, and the foetuses fitted with electrodes. The umbilical cord was blocked for most of them, and half were treated with a test drug. Mothers and unborn lambs were killed three weeks later.

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Testing the combination of drugs for congestive heart failure treatment

Sheep were anaesthetised and subjected to surgery. Electrodes were used to pace their hearts faster while testing the effect of different drugs.

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Testing the best way to deliver gene therapy drugs

Sheep were anaesthetised. Their heads were drilled into, and their brains injected with test drugs. They were killed after three weeks.

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Testing the potency of pneumonia vaccines for sheep

Lambs were vaccinated twice, and regular blood samples were taken for 34 weeks.

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Testing the effects and wash-out of painkillers

Lambs were treated with different painkillers or not at all before tail docking and castration. Their behaviour was monitored.

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Developing “hyperimmune” milk

Sheep were injected with Covid-19 vaccines, and regular blood samples were taken. Some were mated and gave birth to sample their milk, too.

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Studying the genetics of Batten disease on chimeric lambs

Sheep foetuses were removed. After swapping cells between them, they were inserted into other ewes. Lambs born were subjected to X-rays and, at one to three years old, were bled out for dissection.

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Testing pacemaker adjustments

After causing them heart failure, sheep were surgically fitted with pacemakers and measurement devices. Those who survived the procedures were killed after six months.

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Studying methane emission and meat quality

Sheep were bred for high and low methane emissions. Almost 2,000 were put through emission measurements. Over 17,000 were slaughtered.

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Studying the effect of chemicals in normal and high blood pressure

Sheep were surgically fitted with a clip around an artery, or they served as control. Measuring devices were added before injecting different chemicals into the hearts of the conscious sheep.

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Comparing muscle repair success with and without weeks of delay

Ewes were anaesthetised, and one side of a pelvis muscle was detached. After several weeks, the muscle was repaired. Gait was evaluated before all were killed.

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Comparing different designs of dental implants

Sheep were anaesthetised. One leg bone was exposed and fitted with several implants. After 12 weeks, all were killed.

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Trying to model human brain injuries

To study changes in different areas of the brain after brain injuries. Sheep were used to study the effects of traumatic brain injuries in humans.

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Testing efficiency of strip-sowing 1080 bait

The toxin ‘1080’ was distributed as complete coverage and in a strip pattern. Effects on the wild rabbit numbers were evaluated.

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Testing new formulations of eye medication

The eyes of albino rabbits were treated with different medications. At regular intervals, several of them were killed.

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Taking blood samples over several days

Two New Zealand white rabbits were anaesthetised and restrained. Catheters were put into their ear veins to inject a solution and take regular blood samples.

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Harvesting rabbit caecum for more lab tests

Domestic dwarf rabbits were anaesthetised, their caecum was cut out, and then they were killed.

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Using rabbits as a model for human atherosclerosis

NZ White rabbits were fed pellets with or without added cholesterol for 10 weeks. They were killed with anaesthetic and taking blood from their heart until it stopped.

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Testing new drug formulations

NZ White rabbits were given a new drug formulation or ketamine. Righting reflex, paw withdrawal, and blood parameters were checked every minute.

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Infecting rabbits with a virus to have more samples of it

Samples of dead wild rabbits were taken to collect virus material. The virus was then used to infect rabbits and analyse their tissue.

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Injuring the sinus tract to test medication

NZ White rabbits were anaesthetised, and the sinus tracts in their nose were purposely injured to the bone. Two weeks after treatment, they were killed.

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Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

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Testing new drug formulations

Rats and rabbits were injected with a new anaesthetic, pinching their paw repeatedly to measure reflexes. Rats were giving the medication until they died.

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Testing the behaviour of a drug in rabbits’ blood

NZ White rabbits were infused with different medications, and blood samples were taken regularly for 24 hours.

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Testing a new drug delivery formulation

NZ White rabbits were injected with a radioactive solution, wrapped tightly, and recorded this way for 90min.

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Placing metal into rabbits’ jaws

NZ White rabbits were anaesthetised, and metal spheres were placed into their jaws. X-rays were taken to measure bone growth.

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Using rabbits as glaucoma surgery model

The eyes of NZ White rabbits were surgically opened and treated with different solutions. At intervals, some were killed to analyse the eye tissue.

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Monitoring vital signs of rabbits during intercourse

NZ White rabbits were anaesthetised and implanted with devices to measure vital signs. They were then monitored during intercourse.

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Harvesting rabbit caecum for lab tests

Domesticated rabbits were anaesthetised. Part of their digestive tract was removed, and then they were killed.

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