Cattle

Cattle are one of the most used animals for science in NZ. Learn about the many ways they are used!

Thousands of cattle are used for scientific purposes in Aotearoa every year. In fact, they have been one of the most commonly used animals in NZ science since 1989!

This sadly makes sense when you consider how widely they are exploited for their milk and their bodies.

The species of cattle is simplified to cows by many people. Actually, only the mothers are called cows:

  • Heifers are female cattle before they become mothers.
  • Calves are their babies.
  • The males are referred to as bulls (or steers if castrated).
Animal agriculture:

Thousands of cattle are used in Aotearoa every year in research aimed at trying to sustain, enhance and make more money for the animal agriculture industry.

Examples include research into:

1. Decreasing their negative impact on the environment - a cow on its own won't create a huge impact but because we have bred so many cattle in NZ, their collective impact is huge!

  • Cattle have been put in respiration chambers so the amount of methane they produce can be measured. Researchers have also glued urine sensors around their vulva to try and investigate ways of reducing the amount of nitrogen produced in their urine (methane and nitrogen can create negative impacts on the environment).

2. Increasing the survival rate of calves - not for the calves themselves but so the animal agriculture industry doesn't lose as much money.

3. Learning more about the fertility of cows (i.e., trying to improve artificial insemination and reduce the rest time in-between pregnancies for cows). Again, this research is not done for the cows themselves but so they be made pregnant as often as possible so that more money can be made from their exploitation.

4. Genetic modification to try and create more desirable traits in cattle (i.e., genetically modifying cows to change the properties of their milk).

5. Diseases that cattle on farms often get such as lameness, mastitis (a common infection of the udder in dairy cows) and fungal and parasitic infections. This type of research often involves making the animals sick on purpose.

6. Ways of housing and keeping large numbers of cattle on farms (i.e., research into bedding, floor types, shelter, shade and hygiene practices).

7. Trying to find more “humane” slaughter methods (i.e., investigating what type of gas kills piglets the quickest and if stunning animals before killing them creates less of a pain response).

8. Different types of pain relief for standard procedures in the animal agriculture industry (i.e. dehorning, castration, C-section).

9. Safety tests for chemicals and animal remedies, including medications, supplements and fertilizers.

10. Increasing milk or muscle (beef) production (i.e., feeding cattle different additives and measuring how its digested).

Fistulation: Cattle with holes cut into their bodies

For decades, researchers have artificially created fistulas (also known as cannulas) in ruminant animals such as cattle, sheep and deer. These are essentially window-like holes in the side of an animal's body.

Fistulas are tubes that are created surgically to connect a cow or sheep’s stomach to her skin. The outside of the fistula is covered with a plastic cap that can be opened by scientists to remove stomach contents for analysis or introduce foreign substances.

It is a painful procedure and cows are still suffering from the intrusive surgery up to 11 days after the surgery. Learn more here.

Additional calf exploitation - the calf blood industry

Calves and calf foetuses are killed, and the blood is drained from their bodies to be used in other research.

There are two main types of calf blood products: Fetal bovine serum and New Born Calf Serum.

Fetal bovine serum is taken from foetuses that have been removed from their mothers in slaughterhouses after they have been killed. A needle is injected into the foetus’ heart, and the blood is pumped out. The foetuses have to be alive during this so that their blood comes out easier. They also have to be at least three months into the gestation period to ensure that their heart is large enough to puncture.

Newborn Calf Serum is sourced similarly; calves who are 20 days old or younger have their heart punctured and are bled to death.

These products are used as a media base and growth supplement in many different types of research.

In the news

Mycoplasma Bovis: "Researchers will measure how M. Bovis impacts infected animals and herds, including physical signs, effects on milk yield and quality, weight gain in cattle, and the duration of these effects." Read more.

Cow shock collars: "Animals wear GPS-enabled collars that identify their location relative to invisible fence lines created on a digital farm map. The animals are trained to be guided by audio prompts (beeps) from the collars when required. As an animal gets close to a virtual fence, a series of beeps alerts them to the fence boundary. If they cross the fence line, they receive a "disincentive", a mild electric shock, and are guided back inside the line." Read more.

Bobby calves: Bobby calves (male calves of dairy cows) are normally unwanted by the dairy industry. Researchers are cross-breeding dairy cows with beef breeds so that bobby calves can be killed and eaten after a year, rather than being killed as "excess" after 4 days. Read more

Climate change: AgResearch scientists have been given $10 million to develop cattle better adapted to warmer temperatures and to lower methane emissions. Read more.

Places that use cattle for science in NZ include universities such as Lincoln University (who have their own research dairy farm) and Massey University (they also have their own dairy farms), private companies such as Abacus Bio Limited and Cognosco, crown institutes such as AgResearch, industry bodies such as Dairy NZ and by other organisations and individuals.

Cattle used for science in NZ are sourced from commercial establishments, farms, public sources, breeding units and other sources.

Discover real-life examples of how cattle have been used in NZ below!
References:

Studying selenium metabolism

Cats and dogs were fed diets with different selenium supplementation for three weeks in individual metabolic chambers. A liver biopsy was taken under anaesthesia.

Publication Link

Monitoring wild cats via GPS collar

Wild cats were caught and fitted with GPS collars. After an average of 9.75 days, there were recaptured to retrieve the collars.

Publication Link

Testing new toxin against stoats and wild pets

Dogs, cats and stoats were fed different versions of toxic bait. Symptoms and time of death were monitored. Four dogs and two cats survived, but their fate is not stated.

Publication Link

Testing the efficacy and shelf-life of a toxin

Captive wild cats were used to compare the efficacy of different toxin formulations and the effect of more extended bait storage. Cats were fed the toxin bait or pipette-fed toxin directly as control. Symptom onset and time of death were monitored.

Publication Link

Studying the genes for hairyness

The hairiness of male and female cattle was rated. Some animals had their rectal temperature taken repeatedly, and some were shut in a hot room for two hours to make them sweat. Eight calves were killed to take brain samples.

Publication Link

Optimising fertility treatment

Young female cattle were treated with different hormonal injections to control their fertility cycle. Around ten rectal ultrasounds were done on each of them within 11 days, and several blood samples were taken in the next month. All but nine were artificially inseminated. The nine animals showed no fertility signs and were therefore useless for the study and the industry.

Publication Link

Trying out a health test for breeding bulls

Breeding bulls were infected with a skin fungus that usually results in a dangerous build-up in the gall and eczema. Through a special diet, bulls can be tested for their reactions via repeated blood samples and ranked for their genetic quality.

Publication Link

Testing a vaccine against miscarriage

Younger and older pregnant cattle were injected with a new vaccine against a parasite or just control solution. Skin reactions to the injection were checked, and blood samples were taken. Farmers reported miscarriages when they happened, and dead foetuses were collected if possible. If female calves were born, blood samples were taken from them, too.

Publication Link

Studying Johne’s disease

Some female calves of a group were infected with bacteria causing life-threatening sickness. Poo samples were collected directly from the rectum of all calves every other month. Half were killed to be dissected at 7 months, the rest at 15 months.

Publication Link

Studying Johne’s disease bacteria

Blood samples were taken from sick dairy cows who were sent to slaughter to see if their immune system was even putting up a fight. After slaughter, organ samples were taken.

Publication Link

Finding a gene to increase casein in milk

Breeding bulls were evaluated on their quality by judging, breeding, and milking their daughters. No exact numbers are stated how many lived to the end of the study (5 lactations).

Publication Link

Testing a new way to treat liver flukes

Young cattle were infected with liver flukes. They were treated with different medications or left untreated. Regular blood samples were taken from all animals for three weeks, and they were killed ten weeks later.

Publication Link

Studying effects of stunning before slaughter

Calves and sheep were anaesthetised. Some got 70-volt shocks to the shoulder. Others had a nerve exposed and stimulated before being stunned or cutting their throat.

Publication Link

Measuring brain reactions to stunning after killing

Calves were fasted for 24 hours and then anaesthetised. They were killed by their throats being cut, followed by stunning while measuring EEG/ECG (electronic heart and brain activity) and blood pressure.

Publication Link

Measuring brain reactions to stunning

Calves were fasted, anaesthetised and stunned with a non-penetrative bolt while being monitored for their response. After measurements were taken, they were killed.

Publication Link

Studying brain reactions to cutting blood vessels or neck tissue

Calves were anaesthetised, and their throat blood vessels exposed. While monitoring the brain“s activity (EEG) and blood pressure, either only the blood vessels or only the neck tissue was cut. The latter animals were then killed, too.

Publication Link

Measuring if being slaughtered is unpleasant

Calves were fasted, anaesthetised, and killed by cutting their throat. EEG and ECG (recording electronic heart and brain activity) were measured with electrodes in the head.

Publication Link

Measuring brain reactions to pain

Twenty calves were fasted and anaesthetised. Their horn buds were removed with a scoop, and pain response of the heart and brain with and without pain blockers.

Publication Link

Testing mastitis treatments

Dairy cows with an udder infection were treated with different antibiotic injections. Milk samples were taken to monitor results.

Publication Link

Trying to clone cows with more valuable milk protein

The genetic material of a cow foetus was manipulated and cloned into several cows. When they were less than one year old, they were injected with hormones to produce milk for sampling.

Publication Link

Analysing Greyhound race injury statistics

Historical data on Greyhound races between 2014 and 2019 were analysed. Injuries and deaths were investigated.

Publication Link

Using bones of euthanised shelter dog

Cadavers of dogs killed at an animal shelter were donated. Holes were drilled into leg bones and fitted with screws.

Publication Link

Investigating farm dogs for four years

Working farms dogs were examined regularly for four years. Health problems and fate were recorded.

Publication Link

Transplanting faeces as diarrhoea treatment

A dog with diarrhoea was treated with laxatives and warm water before a faeces sample from a healthy dog was inserted into his colon. Samples were taken before and after.

Publication Link

Testing the eyes of working dogs

Eye examinations were performed on working sheep dogs. Medication for pupil dilation was given, and faeces samples were taken from most dogs.

Publication Link

Analysing dog movements

Colony dogs were prepared with reflective markers and an activity collar. Their movements on a treadmill at various speeds were recorded.

Publication Link

Testing the effect of diet on farm dog performance

Working dogs were fed a diet very high or very low in carbohydrates. Their blood glucose and activity were monitored three times over four days each.

Publication Link

Testing a parasite treatment

After a pilot study with just one dog, six more were given an experimental parasitic treatment. Regular blood samples were taken through a catheter.

Publication Link

Teaching dogs to smell out catfish

Five pet dogs were trained over several months to identify catfish and goldfish smell in water samples.

Publication Link

Testing different combinations of pain meds

Eight dogs are treated with four different combinations of the test drugs in random order with two-week breaks in between. Two catheters are placed in leg veins (for drug injection and blood samples). For the test, dogs are fasted for 12 hours and anaesthetised. EEG is recorded with electrodes near the brain to measure response to electric shocks. Regular blood samples are taken for 8 hours.

Publication Link

Studying medical data of cat and dog CT-imaging

Medical data from cats and dogs were gathered, and animals that had been euthanised for other reasons were examined.

Publication Link

Teaching dogs to smell out koi carps (2019)

Three pet dogs were trained over several months to identify koi carb smell in water samples.

Publication Link

Testing working dogs for internal parasites

Faeces and blood samples were taken from working farm dogs.

Publication Link

Testing fluid management of dogs during anaesthesia

Dogs were anaesthetised. Their heart activity was measured while hey were injected with calculated amounts of fluid.

Publication Link

Trying to make rat poison unattractive for dogs

Dogs were fasted overnight and then given two food bowls with different kinds of repellent on one of them.

Publication Link

Surveying respiratory disease in racing Greyhounds

Laboratories sent in serum samples of dogs for analysis. Additionally, 17 racing Greyhounds were tested.

Publication Link

Studying how viruses spread in fish

Fish were caught with nets and killed.

Publication Link

Using fish to study the impacts of Climate Change

Fish were either bought or caught and killed so that they could be dissected.

Publication Link

Overfeeding Zebrafish to learn about obesity

Normal and transgenic zebrafish were fed normally or way too much. The fish were taken out of the water for glucose tests and blood samples.

Publication Link

Studying gut bacteria in fish

Nine fish were caught by underwater spearing and killed so that samples could be collected from their digestion tracts.

Publication Link

Studying the sleep of sharks

Sharks were caught and kept in outside tanks. For the experiments, they weren't fed for at least 4 days, of which they spent 3 days in a measuring chamber not much bigger than the shark. Oxygen consumption and behaviour were continuously recorded for the last 24 hours.

Publication Link

Infecting fish larvae as a potential model for humans

Zebrafish larvae were injected with bacteria to test how their immune system responds. This was repeated to test how well the immune system reacted and how long the effect lasts.

Publication Link

Finding a “growth gene” in snappers

Snappers were caught from the wild and bred. Around eighty-thousand of their offspring were hatched and raised. At regular “grading” events, injured and deformed fish were disposed of. At just under a year old, around twenty-two-thousand were left and transported to a sea pen, where they were raised to 17.5 months old before harvesting.

Publication Link

Testing how much fat you can feed fish

Fish in aquaculture were divided into groups and fed diets with different fat content. Fish were anaesthetised and faeces samples squeezed out of them.

Publication Link

Testing fish for mercury contamination

Wild fish were caught, measured and frozen to be analysed.

Publication Link

Measuring how stress affects fish

Fish were exposed to chronic stress for four weeks, while 57 non-stressed animals were kept as a control. Signs of stress were noted. At the end of the experiment, all were chilled to death.

Publication Link

Exposing fish to herbicides

Zebrafish were kept in tanks that were contaminated with different herbicide concentrations for 10 days. They were then mated to herbicide-exposed or control fish. Both generations were tested on behavioural changes at around 4 months of age. 24 fish per treatment were killed and dissected.

Publication Link

Testing supplements as protection from toxins in over 1,000 fish embryos

Embryos were harvested and kept in Petri dishes for toxicity and treatment tests. Embryos were treated with an antioxidant, a gold salt or both on the first day, and abnormal development was measured on day 5.

Publication Link

Studying effects of drying rivers on mudfish

Water depth and quality were measured at 24 different sites. Several traps for fish and invertebrates were set at 8 visits, sampling and mostly killing the caught animals (including 15 individuals of the endangered Kōwaro).

Publication Link

Studying bacterial spread in fish larvae

Bacteria were genetically modified and made fluorescent. Zebrafish were bred, and their larvae were infected with the bacteria. The fish were killed for analyses or used for live imaging under a microscope (and then killed, most likely).

Publication Link

Investigating effects of invasive fish removal

Using fyke nets and electrofishing, fish were caught on four occasions. Fish were marked with fin clippings around one big removal event where 3 tonnes of fish were caught. In recaptures a week after each marking event, invasive fish caught were killed after the examination.

Publication Link

Studying fish life cycles

Fish were sedated and their blood and ovarian tissue were sampled three times.

Publication Link

Questioning vets on pain management

Veterinarians completed a questionnaire regarding pain and pain management in rabbits and guinea pigs.

Publication Link

Testing nerve reactions to electric stimulation

Young guinea pigs were bled to death. Specific nerves were removed and experimented on.

Publication Link

Studying short-sightedness

Guinea pigs had one eye covered for two weeks before increasing their eye pressure surgically and kill them.

Publication Link

Measuring nerve reactions to gases

Guinea pigs were anaesthetised, and their windpipe and blood vessels were cannulated. They were exposed to different gases and cyanide while measuring breathing and nerve activity.

Publication Link

Studying how anaesthesia affects breathing and heart

Guinea pigs were put in airtight chambers to test the effects of low oxygen. Some were surgically fitted with tubing so blood samples could be taken during the tests. In the end, all were killed.

Publication Link

Studying compensation after inner ear destruction

Guinea pigs were anaesthetised, and their inner ear was destroyed with a drill. Videos were made for over two days of their balance recovery.

Publication Link

Killing pregnant guinea pigs for tissue cultures

Pregnant guinea pigs were anaesthetised at specific time points of their pregnancy, including during labour, to then remove the uterus for tissue culture experiments.

Publication Link

Testing how oxytocin injections cause contractions

Pregnant guinea pigs were surgically implanted with electrodes on or near the uterus. They were injected with oxytocin in specific doses and timeframes, and the effects were measured.

Publication Link

Harvesting testicles for studies

Male guinea pigs were killed with CO2 to remove their testicles for experiments.

Publication Link

Testing a new tuberculosis vaccine

A new tuberculosis vaccine was tested by injecting guinea pigs with the bacteria, either with or without prior vaccination. After several weeks, all were killed.

Publication Link

Testing how heart calcium metabolism is different in species

Guinea pigs and rats were decapitated, and their hearts were quickly removed to study them.

Publication Link

Testing influences on the rate of a dissected heart

Albino guinea pigs were anaesthetised and dissected before they were killed.

Publication Link

Confirming the correlation of energy storage and stress in the inner ear fluid

Guinea pigs were anaesthetised and artificially ventilated. Ear fluid samples were taken through a hole in the skull, while exposing them to noise or lack of oxygen.

Publication Link

Comparing natural and genetically altered tuberculosis strains

Guinea pigs were infected with tuberculosis strains after being injected with bacterial proteins beforehand. In the end, all guinea pigs were killed and dissected.

Publication Link

Comparing effects of anaesthetics on breathing and heart rate

Guinea pigs, rabbits and rats were anaesthetised, and a tube was put into their windpipe through the neck. They were made to breathe anaesthetic gas.

Publication Link

Researching scoliosis genes

Transgenic mice with a specific gene defect were mated. Pregnant mice were at several time points. The unborn babies were taken, skinned, and gutted to stain their skeletons for better pictures.

Publication Link

Studying hormone influences on obesity and fertility

Transgenic mice were bred to have diabetes symptoms. Together with control mice, they were fed a normal or a high caloric diet and compared for their fertility over 150 days.

Publication Link

Testing a new stroke treatment

Mice were squeezed into plastic cones, and test drugs were dripped on their nose. An artificial stroke was caused by injecting a chemical into their brain. Before and after, mice had to perform behavioural tests. All were then killed to take their brains.

Publication Link

Testing another new stroke treatment

Mice were operated on several times. They were made to experience an artificial stroke, were later injected with a possible treatment, and then were injected with a marker. The mice had their memory tested before they were killed.

Publication Link

Testing prostate cancer drugs

Mice were anaesthetised, and their prostate was injected with cancer cells or a control solution. A 42-day treatment course started three weeks later with different treatment drugs and control solutions. In the end, all mice were killed.

Publication Link

Testing a heart attack treatment

Mice were trained to eat jelly and then subjected to an artificial heart attack. They received either a new drug or a control substance. Regular heart ultrasounds were performed before they were killed and dissected.

Publication Link

Studying ovary problems caused by testosterone

Transgenic mice were implanted with a capsule containing either hormones or not. Vaginal smears were done for several weeks, and serial blood tests were performed twice. In the end, all mice were killed.

Publication Link

Testing an Autism treatment on transgenic mice

Mice were genetically modified to show "autism-like" symptoms. Together with control animals, they were either fed normally or with a high-zinc diet. Invasive behavioural tests were performed. At least some, likely all, were killed.

Publication Link

Comparing transgenic mice and humans

Mice were anaesthetised, and their body composition was measured several times. Their grip strength and balance were tested with lab equipment. In the end, all mice were killed.

Publication Link

Testing a new stroke drug for better dexterity

Transgenic mice were anaesthetised, and an artificial stroke was caused. They then received either a test drug or a control solution. After recovery, their food was limited to test their fine motor skills every other week. After two months, they were killed.

Publication Link

Testing migraine drugs

Mice were injected with potential migraine drugs and anaesthetised. Ultrasound imaging of their ears was taken. One ear was rubbed with capsaicin to record the increased blood flow and compare different drugs, doses, and time points.

Publication Link

Killing rats and mice for tissue

Rats and mice were anaesthetised, and their necks were broken. Their tissue was then used for research.

Publication Link

Studying Alzheimer’s and stroke symptoms

One group of transgenic mice were bred and killed at either four or 12 months of age by flushing their hearts. Another group was anaesthetised and caused to have a stroke. They were killed the same way.

Publication Link

Testing Alzheimer’s treatment on mice

Transgenic and “normal” mice were injected with a special protein and a chemical to mark new brain cells that may have been produced.

Publication Link

Testing a new Alzheimer’s drug

Newborn mice were killed to collect brain tissue. Adult mice were used to test drug reactions. They were anaesthetised twice; to inject the drugs and to flush their hearts and take their brains.

Publication Link

Testing if anaesthesia affects the sleep–wake cycle when combined with light treatment

Mice were kept on a 12-hour light/dark cycle and then switched to total darkness. During this time, they were exposed to light once, either with or without anaesthesia. The effect on their activity cycles was monitored. In the end, all were killed.

Publication Link

Harvesting colon tissue for laboratory tests

Pigs were killed and their colon tissue was used for laboratory testing.

Publication Link

Testing if pigs can be fed by-products from biofuel and food processing

Pigs were fed a standard diet or a diet containing by-products from other industries. They were slaughtered to compare meat growth and quality.

Publication Link

Studying starch digestion in pigs to try and model humans

Pigs were fed different diets containing durum wheat or rice. Some had regular blood samples taken through a catheter. All the animals were killed at the end.

Publication Link

Validating a treatment for stomach muscle dysfunctions

Pigs were anaesthetised, their bellies were opened, and electrodes were placed on their stomach walls before and after damaging some stomach tissue with heat. All pigs were killed.

Publication Link

Assessing pigs as digestion models for humans

Titanium tubes were implanted into pigs’ intestines. Digested food was collected through the tube for 9 hours.

Publication Link

Testing the effect of different species’ milk on brain gene expression

Piglets were fed different kinds of milk from other species for 15 days. They were killed to dissect their brains.

Publication Link

Testing transmitter implantation on wild pigs

Wild pigs were captured, and three different tracking devices were fixed to or implanted into each one. After 104 days, they were tracked down and killed.

Publication Link

Investigating oxygen content in the gut

Pigs were fed diets with different or no protein sources as a control. After a week, all were killed.

Publication Link

Testing a UV treatment for bacterial eye infection

Pigs’ eyes were acquired for testing a new treatment, followed by tests on live mice, most of whom were killed.

Publication Link

Testing the effect of different species’ milk on protein digestion

Piglets were fed different kinds of milk from other species for 15 days. They were killed to dissect their stomachs.

Publication Link

Testing the strain on a temporary surgical implant

A surgical implant was screwed to a severed pig head, and measurements were taken via laser scanning.

Publication Link

Investigating intestine movements

Young pigs and NZ White rabbits were anaesthetised. A part of their intestine was pulled out far enough to record its movements and signalling.

Publication Link

Harvesting rabbit and pig eyes for lab tests

The eyes of slaughtered rabbits and pigs killed for experiments were used to analyse the structure of the cornea.

Publication Link

Harvesting eyes for lab tests

The eyes of pigs and rabbits killed for experiments were used to analyse the structure of the cornea.

Publication Link

Testing a treatment for stomach muscle dysfunctions

Pigs were anaesthetised, their bellies were opened, and electrodes were placed on their stomach walls before and after damaging some stomach tissue with heat. All pigs were killed.

Publication Link

Testing how electric stimulation affects stomach movements

Nine pigs were anaesthetised, their bellies were opened, and electrodes were placed on the stomach walls. Electric stimulation tests were performed before the pigs were killed.

Publication Link

Studying how ageing affects brain chemistry

Rats were kept in germ-free, individual cages before being killed. Their brains were used for tests.

Publication Link

Studying teen binge drinking

Young rats were force-fed alcohol repeatedly. Each time, blood samples were taken, and some were killed to take their brains after each alcohol day. The remaining rats were put through behavioural tests a few months later.

Publication Link

Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

Publication Link

Testing medications for drug addiction

Rats were taught to inject themselves with cocaine when they pressed a lever. Through many cycles of establishment and withdrawal, medications were tested for their effect on drug-seeking behaviour. Other rats were tested for their activity level on cocaine with or without medication. Some were put into water-filled cylinders to examine if medication influences how long they swim.

Publication Link

Testing effects of meth on brain protein

Rats were taught to inject themselves with meth or a saline solution when they pressed a lever. After 20 days, there were two weeks of abstinence. In the end, all were killed to dissect their brains.

Publication Link

Testing new drug formulations

Rats and rabbits were injected with a new anaesthetic, pinching their paw repeatedly to measure reflexes. Rats were giving the medication until they died.

Publication Link

Testing blood pressure drugs against seizures

Rats were implanted with devices to measure heart and brain activity through induced seizures without being anaesthetised. They were killed two days later, and their hearts were taken.

Publication Link

Studying the effect of prolactin on the brain

Virgin rats and rats who recently gave birth had a cannula (tube) placed in their brain and were injected with medication. They were injected with prolactin after two days and killed an hour later to dissect their brains.

Publication Link

Testing a surgical treatment for hypertension with diabetes

Transgenic rats were injected to develop diabetes. Their kidney nerves were surgically destroyed. They were restrained for measurements and sampling regularly. In the end, they were all killed.

Publication Link

Testing a new pain medication

Rats were operated on to cause pain build-up in their hind leg. After 10 days, they were injected with different variations of a drug or just a control solution. The effect was tested by poking their hurting leg and having them balance.

Publication Link

Trying to study depressants and antidepressants

Rats were kept isolated or in groups for nine weeks. They were injected with different drugs and put through behavioural tests (the notorious Forced Swim Test, among others). In the end, all were killed.

Publication Link

Studying how anaesthetics affect intestine movement

Guinea pigs and rats were anaesthetised, then dissected, and then killed, in that order.

Publication Link

Studying hormone sensitivity of the brain

Female rats were mated, gave birth and cared for their babies for three weeks. They had prolactin injected below the skull. They were killed, and their brains were removed.

Publication Link

Harvesting rabbit and rat hearts for lab tests

NZ White rabbits and rats were killed to use their hearts in lab tests.

Publication Link

Testing digestion of a pig food

Rats were fed a pig food and killed to examine their intestines.

Publication Link

Testing how heart calcium metabolism is different in species

Guinea pigs and rats were decapitated, and their hearts were quickly removed to study them.

Publication Link

Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

Publication Link

Using sheep to try and model how well humans will heal after dental surgery

Sheep were anaesthetised, three teeth were pulled, and the sockets were treated differently. For months, regular samples were taken from the healing wounds before all sheep were killed.

Publication Link

Preclinical testing of a gene therapy for Batten disease

Sheep with and without a specific gene mutation were checked and scanned regularly for nine months. Affected sheep received gene therapy at different ages. Treated sheep were killed.

Publication Link

Testing if blocking a cell signal can prevent foetal brain injury

Pregnant sheep were anaesthetised, and the foetuses fitted with electrodes. The umbilical cord was blocked for most of them, and half were treated with a test drug. Mothers and unborn lambs were killed three weeks later.

Publication Link

Testing the combination of drugs for congestive heart failure treatment

Sheep were anaesthetised and subjected to surgery. Electrodes were used to pace their hearts faster while testing the effect of different drugs.

Publication Link

Testing the best way to deliver gene therapy drugs

Sheep were anaesthetised. Their heads were drilled into, and their brains injected with test drugs. They were killed after three weeks.

Publication Link

Testing the potency of pneumonia vaccines for sheep

Lambs were vaccinated twice, and regular blood samples were taken for 34 weeks.

Publication Link

Testing the effects and wash-out of painkillers

Lambs were treated with different painkillers or not at all before tail docking and castration. Their behaviour was monitored.

Publication Link

Developing “hyperimmune” milk

Sheep were injected with Covid-19 vaccines, and regular blood samples were taken. Some were mated and gave birth to sample their milk, too.

Publication Link

Studying the genetics of Batten disease on chimeric lambs

Sheep foetuses were removed. After swapping cells between them, they were inserted into other ewes. Lambs born were subjected to X-rays and, at one to three years old, were bled out for dissection.

Publication Link

Testing pacemaker adjustments

After causing them heart failure, sheep were surgically fitted with pacemakers and measurement devices. Those who survived the procedures were killed after six months.

Publication Link

Studying methane emission and meat quality

Sheep were bred for high and low methane emissions. Almost 2,000 were put through emission measurements. Over 17,000 were slaughtered.

Publication Link

Studying the effect of chemicals in normal and high blood pressure

Sheep were surgically fitted with a clip around an artery, or they served as control. Measuring devices were added before injecting different chemicals into the hearts of the conscious sheep.

Publication Link

Comparing muscle repair success with and without weeks of delay

Ewes were anaesthetised, and one side of a pelvis muscle was detached. After several weeks, the muscle was repaired. Gait was evaluated before all were killed.

Publication Link

Comparing different designs of dental implants

Sheep were anaesthetised. One leg bone was exposed and fitted with several implants. After 12 weeks, all were killed.

Publication Link

Trying to model human brain injuries

To study changes in different areas of the brain after brain injuries. Sheep were used to study the effects of traumatic brain injuries in humans.

Publication Link

Testing efficiency of strip-sowing 1080 bait

The toxin ‘1080’ was distributed as complete coverage and in a strip pattern. Effects on the wild rabbit numbers were evaluated.

Publication Link

Testing new formulations of eye medication

The eyes of albino rabbits were treated with different medications. At regular intervals, several of them were killed.

Publication Link

Taking blood samples over several days

Two New Zealand white rabbits were anaesthetised and restrained. Catheters were put into their ear veins to inject a solution and take regular blood samples.

Publication Link

Harvesting rabbit caecum for more lab tests

Domestic dwarf rabbits were anaesthetised, their caecum was cut out, and then they were killed.

Publication Link

Using rabbits as a model for human atherosclerosis

NZ White rabbits were fed pellets with or without added cholesterol for 10 weeks. They were killed with anaesthetic and taking blood from their heart until it stopped.

Publication Link

Testing new drug formulations

NZ White rabbits were given a new drug formulation or ketamine. Righting reflex, paw withdrawal, and blood parameters were checked every minute.

Publication Link

Infecting rabbits with a virus to have more samples of it

Samples of dead wild rabbits were taken to collect virus material. The virus was then used to infect rabbits and analyse their tissue.

Publication Link

Injuring the sinus tract to test medication

NZ White rabbits were anaesthetised, and the sinus tracts in their nose were purposely injured to the bone. Two weeks after treatment, they were killed.

Publication Link

Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

Publication Link

Testing new drug formulations

Rats and rabbits were injected with a new anaesthetic, pinching their paw repeatedly to measure reflexes. Rats were giving the medication until they died.

Publication Link

Testing the behaviour of a drug in rabbits’ blood

NZ White rabbits were infused with different medications, and blood samples were taken regularly for 24 hours.

Publication Link

Testing a new drug delivery formulation

NZ White rabbits were injected with a radioactive solution, wrapped tightly, and recorded this way for 90min.

Publication Link

Placing metal into rabbits’ jaws

NZ White rabbits were anaesthetised, and metal spheres were placed into their jaws. X-rays were taken to measure bone growth.

Publication Link

Using rabbits as glaucoma surgery model

The eyes of NZ White rabbits were surgically opened and treated with different solutions. At intervals, some were killed to analyse the eye tissue.

Publication Link

Monitoring vital signs of rabbits during intercourse

NZ White rabbits were anaesthetised and implanted with devices to measure vital signs. They were then monitored during intercourse.

Publication Link

Harvesting rabbit caecum for lab tests

Domesticated rabbits were anaesthetised. Part of their digestive tract was removed, and then they were killed.

Publication Link

With your help we can end animal experimentation in Aotearoa.