Cattle

Cattle are one of the most used animals for science in NZ. Learn about the many ways they are used!

Thousands of cattle are used for scientific purposes in Aotearoa every year. In fact, they have been one of the most commonly used animals in NZ science since 1989!

This sadly makes sense when you consider how widely they are exploited for their milk and their bodies.

The species of cattle is simplified to cows by many people. Actually, only the mothers are called cows:

  • Heifers are female cattle before they become mothers.
  • Calves are their babies.
  • The males are referred to as bulls (or steers if castrated).
Animal agriculture:

Thousands of cattle are used in Aotearoa every year in research aimed at trying to sustain, enhance and make more money for the animal agriculture industry.

Examples include research into:

1. Decreasing their negative impact on the environment - a cow on its own won't create a huge impact but because we have bred so many cattle in NZ, their collective impact is huge!

  • Cattle have been put in respiration chambers so the amount of methane they produce can be measured. Researchers have also glued urine sensors around their vulva to try and investigate ways of reducing the amount of nitrogen produced in their urine (methane and nitrogen can create negative impacts on the environment).

2. Increasing the survival rate of calves - not for the calves themselves but so the animal agriculture industry doesn't lose as much money.

3. Learning more about the fertility of cows (i.e., trying to improve artificial insemination and reduce the rest time in-between pregnancies for cows). Again, this research is not done for the cows themselves but so they be made pregnant as often as possible so that more money can be made from their exploitation.

4. Genetic modification to try and create more desirable traits in cattle (i.e., genetically modifying cows to change the properties of their milk).

5. Diseases that cattle on farms often get such as lameness, mastitis (a common infection of the udder in dairy cows) and fungal and parasitic infections. This type of research often involves making the animals sick on purpose.

6. Ways of housing and keeping large numbers of cattle on farms (i.e., research into bedding, floor types, shelter, shade and hygiene practices).

7. Trying to find more “humane” slaughter methods (i.e., investigating what type of gas kills piglets the quickest and if stunning animals before killing them creates less of a pain response).

8. Different types of pain relief for standard procedures in the animal agriculture industry (i.e. dehorning, castration, C-section).

9. Safety tests for chemicals and animal remedies, including medications, supplements and fertilizers.

10. Increasing milk or muscle (beef) production (i.e., feeding cattle different additives and measuring how its digested).

Fistulation: Cattle with holes cut into their bodies

For decades, researchers have artificially created fistulas (also known as cannulas) in ruminant animals such as cattle, sheep and deer. These are essentially window-like holes in the side of an animal's body.

Fistulas are tubes that are created surgically to connect a cow or sheep’s stomach to her skin. The outside of the fistula is covered with a plastic cap that can be opened by scientists to remove stomach contents for analysis or introduce foreign substances.

It is a painful procedure and cows are still suffering from the intrusive surgery up to 11 days after the surgery. Learn more here.

Additional calf exploitation - the calf blood industry

Calves and calf foetuses are killed, and the blood is drained from their bodies to be used in other research.

There are two main types of calf blood products: Fetal bovine serum and New Born Calf Serum.

Fetal bovine serum is taken from foetuses that have been removed from their mothers in slaughterhouses after they have been killed. A needle is injected into the foetus’ heart, and the blood is pumped out. The foetuses have to be alive during this so that their blood comes out easier. They also have to be at least three months into the gestation period to ensure that their heart is large enough to puncture.

Newborn Calf Serum is sourced similarly; calves who are 20 days old or younger have their heart punctured and are bled to death.

These products are used as a media base and growth supplement in many different types of research.

In the news

Mycoplasma Bovis: "Researchers will measure how M. Bovis impacts infected animals and herds, including physical signs, effects on milk yield and quality, weight gain in cattle, and the duration of these effects." Read more.

Cow shock collars: "Animals wear GPS-enabled collars that identify their location relative to invisible fence lines created on a digital farm map. The animals are trained to be guided by audio prompts (beeps) from the collars when required. As an animal gets close to a virtual fence, a series of beeps alerts them to the fence boundary. If they cross the fence line, they receive a "disincentive", a mild electric shock, and are guided back inside the line." Read more.

Bobby calves: Bobby calves (male calves of dairy cows) are normally unwanted by the dairy industry. Researchers are cross-breeding dairy cows with beef breeds so that bobby calves can be killed and eaten after a year, rather than being killed as "excess" after 4 days. Read more

Climate change: AgResearch scientists have been given $10 million to develop cattle better adapted to warmer temperatures and to lower methane emissions. Read more.

Places that use cattle for science in NZ include universities such as Lincoln University (who have their own research dairy farm) and Massey University (they also have their own dairy farms), private companies such as Abacus Bio Limited and Cognosco, crown institutes such as AgResearch, industry bodies such as Dairy NZ and by other organisations and individuals.

Cattle used for science in NZ are sourced from commercial establishments, farms, public sources, breeding units and other sources.

Discover real-life examples of how cattle have been used in NZ below!
References:

Measuring thickness of blood vessel walls

Colony cats were anaesthetised, and the blood vessels under their tongue were measured with a special hand-held camera.

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Collecting faeces for lab tests

Colony cats were fed different diets for three weeks before their faeces was collected for analyses.

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Surveying caregivers on their cat feeding

New Zealand cat caregivers filled in an online survey about their household demographics and what/how they feed their cats.

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Testing new toxin in Hawke’s Bay (again)

Toxic bait traps were placed on a property in Hawke’s Bay. Cat population changes were monitored with stationary cameras.

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Assessing stress reaction to anaesthesia in cats

Cats were put through several anaesthetic infusions with six-day breaks in between. Regular saliva samples were taken 24 hours before and after, and urine was collected through a wire mesh tray.

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Trialling ready-made toxic bait

Toxic bait stations are set up in a regular pattern in an area and left for two weeks. Trial cameras and tracking tunnels monitor the effect on the population.

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Studying medical data of cat and dog CT-imaging

Medical data from cats and dogs were gathered, and animals that had been euthanised for other reasons were examined.

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Testing if a human diabetes drug might also work in cats

Research cats were placed in individual cages four times (one week each time) and injected with either a diabetes drug or a control solution. Several blood and urine samples were taken.

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Testing a cat food supplement for tooth health

Colony cats were anaesthetised, and all plaque was removed from their teeth. Four weeks later, new plaque build-up was measured.

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Sampling cats for feline immunodeficiency virus (FIV)

Buccal swabs (inside the cheek) were collected from almost 200 cats at 15 veterinary clinics.

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Testing food preferences of cats

Cats were fasted for two hours in the mornings and then presented with different foods (lamb and beef parts) to measure their consumption.

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Monitoring wild cats for a year

Wild cats are trapped and fitted with GPS collars. After one year, they are recaptured and killed.

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Trialling a lighter rifle to kill trapped wild cats

Captured wild cats were shot in the head using an air rifle and were assessed to confirm death by recording the time to loss of heartbeat.

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Testing a predictive marker for cancer survival in cats

Veterinary samples of cats with this form of cancer were analysed and compared with their remaining survival since diagnosis.

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Monitoring outdoor cat behaviour

Privately owned cats with outdoor access were fitted with camera and GPS collars for up to three days.

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Testing a diagnostic for feline coronavirus

Cats with specific symptoms were used to take blood, tissue, and fluid samples. Some blood samples were taken from control cats.

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Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

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Testing a fertility treatment

Cows with fertility problems were treated with hormones for ten days or left untreated. All were then artificially inseminated.

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Testing a supplement for more calcium intake

Pregnant cows were fed with or without a specific feed additive. After birth, all were fed the same diet. Blood samples were taken in the weeks around birth.

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Checking endometritis rates in dairy herds

Some cows in several dairy herds were selected, and their vaginal discharge was measured and sampled. They were then impregnated as per standard agricultural practice.

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Comparing weight gain with different diets

Newborn calves were raised on various milk, pasture, and pellets combinations. They were slaughtered at two years old, and their “quality” was measured.

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Testing pain meds for disbudding

The horn buds of young calves who were slightly sedated were burned off with a hot iron. Half of them received pain meds beforehand, and blood samples were taken before and after. After 24 hours, the second group received pain meds, too.

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Studying Ikeda infection and treatment

Regular blood samples were taken from cows on three different farms. Only some were treated against the parasite. Milk production and fertility were recorded.

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Studying diarrhea infection

New mother cows had blood samples taken. If the sample was negative for a diarrhoea virus, they were sampled again after a while.

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Studying genes for body size

Udders of dairy cows were slightly cut with a scalpel, and a tissue sample was taken with a biopsy needle.

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Testing toxicity of a potential new fertiliser

Pigs were fed toxic bait and monitored until they died.

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Studying stress around birth

Blood samples were taken from cows with a high or low risk of health concerns after birth.

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Studying genetics of a missing tail

Cloned foetuses were implanted into female cattle to research taillessness. Some of them were killed during pregnancy to examine the foetuses. One tailless animal was killed at age 4, and one of the cloned calves died after birth.

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Studying Ikeda (parasite) infection

Blood samples were taken from dairy cows and their calves directly after birth before separating them. After four months, the calves were sampled again.

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Studying Osteoporosis in cows

Young female cattle who had given birth for the first time were sent to slaughter. Half of them had broken bones for between 2 and 10 days. Blood samples were taken before slaughter, and bones were collected after.

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Testing a tuberculosis vaccine

Male calves were infected with bacteria. Two groups were vaccinated before or after the infection, and the third group was left untreated. All were killed and dissected 13 weeks later.

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Testing feeding plans for better immunity after calving

Pregnant cows were fed either a bit too much or a bit too little. Blood samples were taken before, at, and after calving. Researchers also took liver samples with a 20-cm biopsy needle and vaginal samples with a small brush and a scoop at these dates, except for the date of birth.

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Testing dogs’ preception of time

Dogs were trained to press different levers based on their exposure to different types of light.

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Testing working dogs for a gene mutation

Buccal swabs (inside the cheek) were collected from working dogs to analyse their DNA.</p><p id="">Procedure: Buccal samples were collected from 100 working farm dogs. Their owners were approached at gatherings such as Working Dog Trials, veterinary clinics and farms. Swabs were taken under the owner’s care. No adverse effects from the sampling were reported.

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Determining how common E. coli is in pets

Rectal swaps were taken from cats and dogs presented at veterinary clinics, and their caregivers filled out a questionnaire.

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Testing interest of dogs in different kiwi bird items

Dogs were taken to a small area to interact with different items that looked or smelled like kiwi bird. Some dogs had patches of hair shaved off to attach a heart rate monitor.

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Teaching dogs to smell out koi carps (2018)

Five pet dogs were trained over several months to identify the smell of koi carb from water samples.

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Measuring lean body mass of working dogs

Blood samples were taken from dogs, while they were deprived of water for 2 hours.

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Testing a possum poison for other animals’ safety

Dogs were fed dead possum, either whole or minced. Once they got used to eating this, they were fed with possums killed with sodium nitrite, and signs for poisoning were monitored. In the end, all animals were killed and dissected.

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Investigating separation anxiety in Greyhounds

The occurrence of separation anxiety with rehomed Greyhounds was investigated over one year.

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Investigating a muscle weakness disease in dogs

Blood samples were taken from dogs with signs of myopathy within the regular veterinary treatment. A total of 22 of the 86 cases were euthanised.

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Analysing CT scans of dogs

Veterinary data of German shepherd dogs were analysed; most were police dogs.

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Testing if bone marrow is different in different body parts

Dogs were killed, and samples of their bone marrow were taken from different locations on their bodies.

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Practising vet skills on different species

Students are taught anatomy, physiology, animal handling and basic clinical/husbandry skills. Dogs were used in for training in anaesthesia classes.

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Assessing blindness in racing greyhounds

Greyhounds were treated with pupil dilation drops to examine their eyes. Some were brought to a vet clinic for further tests.

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Testing a possum poison for other animals’ safety

Dogs, chickens and wild-caught cats were fed dead possum. Once they got used to eating this, they were fed possums killed with sodium nitrite, and signs for poisoning were monitored.

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Testing nutritional value of new pet food

Cats and dogs were fed a test diet exclusively for several months. Some adults are kept in metabolic chambers for 10 days, and blood samples are taken at the end.

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Scanning spines of dogs in CT

Police dogs and racing Greyhounds were sedated and computed tomography imaging was taken.

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Studying how viruses spread in fish

Fish were caught with nets and killed.

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Using fish to study the impacts of Climate Change

Fish were either bought or caught and killed so that they could be dissected.

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Overfeeding Zebrafish to learn about obesity

Normal and transgenic zebrafish were fed normally or way too much. The fish were taken out of the water for glucose tests and blood samples.

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Studying gut bacteria in fish

Nine fish were caught by underwater spearing and killed so that samples could be collected from their digestion tracts.

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Studying the sleep of sharks

Sharks were caught and kept in outside tanks. For the experiments, they weren't fed for at least 4 days, of which they spent 3 days in a measuring chamber not much bigger than the shark. Oxygen consumption and behaviour were continuously recorded for the last 24 hours.

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Infecting fish larvae as a potential model for humans

Zebrafish larvae were injected with bacteria to test how their immune system responds. This was repeated to test how well the immune system reacted and how long the effect lasts.

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Finding a “growth gene” in snappers

Snappers were caught from the wild and bred. Around eighty-thousand of their offspring were hatched and raised. At regular “grading” events, injured and deformed fish were disposed of. At just under a year old, around twenty-two-thousand were left and transported to a sea pen, where they were raised to 17.5 months old before harvesting.

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Testing how much fat you can feed fish

Fish in aquaculture were divided into groups and fed diets with different fat content. Fish were anaesthetised and faeces samples squeezed out of them.

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Testing fish for mercury contamination

Wild fish were caught, measured and frozen to be analysed.

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Measuring how stress affects fish

Fish were exposed to chronic stress for four weeks, while 57 non-stressed animals were kept as a control. Signs of stress were noted. At the end of the experiment, all were chilled to death.

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Exposing fish to herbicides

Zebrafish were kept in tanks that were contaminated with different herbicide concentrations for 10 days. They were then mated to herbicide-exposed or control fish. Both generations were tested on behavioural changes at around 4 months of age. 24 fish per treatment were killed and dissected.

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Testing supplements as protection from toxins in over 1,000 fish embryos

Embryos were harvested and kept in Petri dishes for toxicity and treatment tests. Embryos were treated with an antioxidant, a gold salt or both on the first day, and abnormal development was measured on day 5.

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Studying effects of drying rivers on mudfish

Water depth and quality were measured at 24 different sites. Several traps for fish and invertebrates were set at 8 visits, sampling and mostly killing the caught animals (including 15 individuals of the endangered Kōwaro).

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Studying bacterial spread in fish larvae

Bacteria were genetically modified and made fluorescent. Zebrafish were bred, and their larvae were infected with the bacteria. The fish were killed for analyses or used for live imaging under a microscope (and then killed, most likely).

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Investigating effects of invasive fish removal

Using fyke nets and electrofishing, fish were caught on four occasions. Fish were marked with fin clippings around one big removal event where 3 tonnes of fish were caught. In recaptures a week after each marking event, invasive fish caught were killed after the examination.

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Studying fish life cycles

Fish were sedated and their blood and ovarian tissue were sampled three times.

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Developing a model for thermal stress in humans

Guinea pig pups were lightly anaesthetised, connected to devices measuring heart activity and breathing, and wrapped in a temperature-controlling blanket. Their body temperature was either forcefully raised or dropped.

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Testing how too much fructose is bad during pregnancy

Female guinea pigs were mated; some were fed additional sugary water until birth. The pups were used for several glucose tolerance tests and X-rays. All pups were killed in the end.

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Testing a seizure medicine for preterm babies

Pregnant guinea pigs were induced to give birth early, to test medication on their pups.

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Testing the effects of sedatives

Young guinea pigs were treated with different sedatives. Their heart rate and blood pressure were measured before and during each treatment.

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Testing an refined way of anaesthesia in guinea pigs

Guinea pigs were made to inhale anaesthetic gases. Different probes were inserted and attached to the animals to measure responses.

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Studying the effect of fructose during pregnancy

Guinea pigs were fed either normally or supplemented with fruit sugar before and during pregnancy until birth. Mothers and pups were tested for glucose tolerance.

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Studying the effects of meth

Guinea pigs were injected with sedatives, caffeine, and later meth. Under anaesthesia, their livers were cut out before they were killed.

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Studying preterm birth effects on the brain

Pregnant guinea pigs were grouped to give birth normally or be induced early. The pups were put through behavioural tests and then killed for dissection.

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Studying trauma and treatment of cochlear implants

After destroying their hearing with noise, guinea pigs were fitted with cochlear implants. Treatment success was tested before they were killed.

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Testing the measurement of pupil reflexes in Alzheimer’s research

Guinea pigs were repeatedly flashed in the eyes with a phone light to record the pupil responses.

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Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

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Investigating mechanisms slowing down the heart rate

Young guinea pigs were injected with blood thinner before being anaesthetised and dissected.

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Testing a device to assess hearing

Young guinea pigs were anaesthetised, electrodes placed under their skin, and their brain's response to sound was measured. All guinea pigs had one ear damaged, some both ears, before all were killed.

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Studying changes in the inner ear due to inflammation

Guinea pigs were injected into the ear with bacteria. Medical scans were done after injecting chemicals, and most were killed for dissection.

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Studying the effects of medication on memory

Guinea pigs were force-fed different drugs and later tested in a water maze before some were killed. Another group was exposed to carbon dioxide and decapitated.

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Studying how anaesthetics affect intestine movement

Guinea pigs and rats were anaesthetised, then dissected, and then killed, in that order.

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Testing motherly instinct towards foster pups

Mice of different “status” (never pregnant, pregnant, new mums) were made to rescue foster pups they didn’t know from several places. Transgenic mice lacking a prolactin brain receptor were tested for anxiety behaviour in the standard elevated-plus-maze.

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Testing new cancer vaccines

Mice were injected with cancer cells, followed by one of several potential vaccines. They were killed when tumours reached a certain size, or it became otherwise inhumane to keep them alive.

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Testing if pregnancy affects the healing of teeth

Pregnant and non-pregnant mice were taken. After the pregnant ones gave birth, all mice were anaesthetised. Some of their teeth were forcefully moved. Two weeks later, all were killed.

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Testing the effect of obesity during pregnancy

Pregnant mice were fed high-fat diets and had their babies removed via caesarean section. The foetuses were decapitated. Other newborn mice were separated to record their calls.

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Testing how motherly mice are

Transgenic mice were compared to “normal” mice on rescuing pups and how they care for their babies. They were mated, gave birth, and then put through behavioural tests involving newborn mice. After a few weeks, they were killed.

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Testing a medicine against drug addiction

Mice's tails were dunked in hot water. Rats were put through cycles of drug-seeking and withdrawal using self-injection of cocaine. Other rats were injected, and their behaviour was tested (with the notorious Forces Swim Test, among others).

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Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

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Testing the viability of xenotransplantation using islet capsules

Newborn piglets were killed for their pancreas. Encapsulated pancreas cells were then implanted into young mice, who were killed later to retrieve the capsules.

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Harvesting colon tissue for laboratory tests

Pigs were killed and their colon tissue was used for laboratory testing.

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Testing if pigs can be fed by-products from biofuel and food processing

Pigs were fed a standard diet or a diet containing by-products from other industries. They were slaughtered to compare meat growth and quality.

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Studying starch digestion in pigs to try and model humans

Pigs were fed different diets containing durum wheat or rice. Some had regular blood samples taken through a catheter. All the animals were killed at the end.

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Validating a treatment for stomach muscle dysfunctions

Pigs were anaesthetised, their bellies were opened, and electrodes were placed on their stomach walls before and after damaging some stomach tissue with heat. All pigs were killed.

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Assessing pigs as digestion models for humans

Titanium tubes were implanted into pigs’ intestines. Digested food was collected through the tube for 9 hours.

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Testing the effect of different species’ milk on brain gene expression

Piglets were fed different kinds of milk from other species for 15 days. They were killed to dissect their brains.

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Testing transmitter implantation on wild pigs

Wild pigs were captured, and three different tracking devices were fixed to or implanted into each one. After 104 days, they were tracked down and killed.

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Investigating oxygen content in the gut

Pigs were fed diets with different or no protein sources as a control. After a week, all were killed.

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Testing a UV treatment for bacterial eye infection

Pigs’ eyes were acquired for testing a new treatment, followed by tests on live mice, most of whom were killed.

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Testing the effect of different species’ milk on protein digestion

Piglets were fed different kinds of milk from other species for 15 days. They were killed to dissect their stomachs.

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Testing the strain on a temporary surgical implant

A surgical implant was screwed to a severed pig head, and measurements were taken via laser scanning.

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Investigating intestine movements

Young pigs and NZ White rabbits were anaesthetised. A part of their intestine was pulled out far enough to record its movements and signalling.

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Harvesting rabbit and pig eyes for lab tests

The eyes of slaughtered rabbits and pigs killed for experiments were used to analyse the structure of the cornea.

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Harvesting eyes for lab tests

The eyes of pigs and rabbits killed for experiments were used to analyse the structure of the cornea.

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Testing a treatment for stomach muscle dysfunctions

Pigs were anaesthetised, their bellies were opened, and electrodes were placed on their stomach walls before and after damaging some stomach tissue with heat. All pigs were killed.

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Testing how electric stimulation affects stomach movements

Nine pigs were anaesthetised, their bellies were opened, and electrodes were placed on the stomach walls. Electric stimulation tests were performed before the pigs were killed.

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Comparing effects of anaesthetics on breathing and heart rate

Guinea pigs, rabbits and rats were anaesthetised, and a tube was put into their windpipe through the neck. They were made to breathe anaesthetic gas.

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Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

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Using sheep to try and model how well humans will heal after dental surgery

Sheep were anaesthetised, three teeth were pulled, and the sockets were treated differently. For months, regular samples were taken from the healing wounds before all sheep were killed.

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Preclinical testing of a gene therapy for Batten disease

Sheep with and without a specific gene mutation were checked and scanned regularly for nine months. Affected sheep received gene therapy at different ages. Treated sheep were killed.

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Testing if blocking a cell signal can prevent foetal brain injury

Pregnant sheep were anaesthetised, and the foetuses fitted with electrodes. The umbilical cord was blocked for most of them, and half were treated with a test drug. Mothers and unborn lambs were killed three weeks later.

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Testing the combination of drugs for congestive heart failure treatment

Sheep were anaesthetised and subjected to surgery. Electrodes were used to pace their hearts faster while testing the effect of different drugs.

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Testing the best way to deliver gene therapy drugs

Sheep were anaesthetised. Their heads were drilled into, and their brains injected with test drugs. They were killed after three weeks.

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Testing the potency of pneumonia vaccines for sheep

Lambs were vaccinated twice, and regular blood samples were taken for 34 weeks.

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Testing the effects and wash-out of painkillers

Lambs were treated with different painkillers or not at all before tail docking and castration. Their behaviour was monitored.

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Developing “hyperimmune” milk

Sheep were injected with Covid-19 vaccines, and regular blood samples were taken. Some were mated and gave birth to sample their milk, too.

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Studying the genetics of Batten disease on chimeric lambs

Sheep foetuses were removed. After swapping cells between them, they were inserted into other ewes. Lambs born were subjected to X-rays and, at one to three years old, were bled out for dissection.

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Testing pacemaker adjustments

After causing them heart failure, sheep were surgically fitted with pacemakers and measurement devices. Those who survived the procedures were killed after six months.

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Studying methane emission and meat quality

Sheep were bred for high and low methane emissions. Almost 2,000 were put through emission measurements. Over 17,000 were slaughtered.

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Studying the effect of chemicals in normal and high blood pressure

Sheep were surgically fitted with a clip around an artery, or they served as control. Measuring devices were added before injecting different chemicals into the hearts of the conscious sheep.

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Comparing muscle repair success with and without weeks of delay

Ewes were anaesthetised, and one side of a pelvis muscle was detached. After several weeks, the muscle was repaired. Gait was evaluated before all were killed.

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Comparing different designs of dental implants

Sheep were anaesthetised. One leg bone was exposed and fitted with several implants. After 12 weeks, all were killed.

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Trying to model human brain injuries

To study changes in different areas of the brain after brain injuries. Sheep were used to study the effects of traumatic brain injuries in humans.

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Testing efficiency of strip-sowing 1080 bait

The toxin ‘1080’ was distributed as complete coverage and in a strip pattern. Effects on the wild rabbit numbers were evaluated.

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Testing new formulations of eye medication

The eyes of albino rabbits were treated with different medications. At regular intervals, several of them were killed.

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Taking blood samples over several days

Two New Zealand white rabbits were anaesthetised and restrained. Catheters were put into their ear veins to inject a solution and take regular blood samples.

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Harvesting rabbit caecum for more lab tests

Domestic dwarf rabbits were anaesthetised, their caecum was cut out, and then they were killed.

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Using rabbits as a model for human atherosclerosis

NZ White rabbits were fed pellets with or without added cholesterol for 10 weeks. They were killed with anaesthetic and taking blood from their heart until it stopped.

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Testing new drug formulations

NZ White rabbits were given a new drug formulation or ketamine. Righting reflex, paw withdrawal, and blood parameters were checked every minute.

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Infecting rabbits with a virus to have more samples of it

Samples of dead wild rabbits were taken to collect virus material. The virus was then used to infect rabbits and analyse their tissue.

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Injuring the sinus tract to test medication

NZ White rabbits were anaesthetised, and the sinus tracts in their nose were purposely injured to the bone. Two weeks after treatment, they were killed.

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Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

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Testing new drug formulations

Rats and rabbits were injected with a new anaesthetic, pinching their paw repeatedly to measure reflexes. Rats were giving the medication until they died.

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Testing the behaviour of a drug in rabbits’ blood

NZ White rabbits were infused with different medications, and blood samples were taken regularly for 24 hours.

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Testing a new drug delivery formulation

NZ White rabbits were injected with a radioactive solution, wrapped tightly, and recorded this way for 90min.

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Placing metal into rabbits’ jaws

NZ White rabbits were anaesthetised, and metal spheres were placed into their jaws. X-rays were taken to measure bone growth.

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Using rabbits as glaucoma surgery model

The eyes of NZ White rabbits were surgically opened and treated with different solutions. At intervals, some were killed to analyse the eye tissue.

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Monitoring vital signs of rabbits during intercourse

NZ White rabbits were anaesthetised and implanted with devices to measure vital signs. They were then monitored during intercourse.

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Harvesting rabbit caecum for lab tests

Domesticated rabbits were anaesthetised. Part of their digestive tract was removed, and then they were killed.

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