Cattle

Cattle are one of the most used animals for science in NZ. Learn about the many ways they are used!

Thousands of cattle are used for scientific purposes in Aotearoa every year. In fact, they have been one of the most commonly used animals in NZ science since 1989!

This sadly makes sense when you consider how widely they are exploited for their milk and their bodies.

The species of cattle is simplified to cows by many people. Actually, only the mothers are called cows:

  • Heifers are female cattle before they become mothers.
  • Calves are their babies.
  • The males are referred to as bulls (or steers if castrated).
Animal agriculture:

Thousands of cattle are used in Aotearoa every year in research aimed at trying to sustain, enhance and make more money for the animal agriculture industry.

Examples include research into:

1. Decreasing their negative impact on the environment - a cow on its own won't create a huge impact but because we have bred so many cattle in NZ, their collective impact is huge!

  • Cattle have been put in respiration chambers so the amount of methane they produce can be measured. Researchers have also glued urine sensors around their vulva to try and investigate ways of reducing the amount of nitrogen produced in their urine (methane and nitrogen can create negative impacts on the environment).

2. Increasing the survival rate of calves - not for the calves themselves but so the animal agriculture industry doesn't lose as much money.

3. Learning more about the fertility of cows (i.e., trying to improve artificial insemination and reduce the rest time in-between pregnancies for cows). Again, this research is not done for the cows themselves but so they be made pregnant as often as possible so that more money can be made from their exploitation.

4. Genetic modification to try and create more desirable traits in cattle (i.e., genetically modifying cows to change the properties of their milk).

5. Diseases that cattle on farms often get such as lameness, mastitis (a common infection of the udder in dairy cows) and fungal and parasitic infections. This type of research often involves making the animals sick on purpose.

6. Ways of housing and keeping large numbers of cattle on farms (i.e., research into bedding, floor types, shelter, shade and hygiene practices).

7. Trying to find more “humane” slaughter methods (i.e., investigating what type of gas kills piglets the quickest and if stunning animals before killing them creates less of a pain response).

8. Different types of pain relief for standard procedures in the animal agriculture industry (i.e. dehorning, castration, C-section).

9. Safety tests for chemicals and animal remedies, including medications, supplements and fertilizers.

10. Increasing milk or muscle (beef) production (i.e., feeding cattle different additives and measuring how its digested).

Fistulation: Cattle with holes cut into their bodies

For decades, researchers have artificially created fistulas (also known as cannulas) in ruminant animals such as cattle, sheep and deer. These are essentially window-like holes in the side of an animal's body.

Fistulas are tubes that are created surgically to connect a cow or sheep’s stomach to her skin. The outside of the fistula is covered with a plastic cap that can be opened by scientists to remove stomach contents for analysis or introduce foreign substances.

It is a painful procedure and cows are still suffering from the intrusive surgery up to 11 days after the surgery. Learn more here.

Additional calf exploitation - the calf blood industry

Calves and calf foetuses are killed, and the blood is drained from their bodies to be used in other research.

There are two main types of calf blood products: Fetal bovine serum and New Born Calf Serum.

Fetal bovine serum is taken from foetuses that have been removed from their mothers in slaughterhouses after they have been killed. A needle is injected into the foetus’ heart, and the blood is pumped out. The foetuses have to be alive during this so that their blood comes out easier. They also have to be at least three months into the gestation period to ensure that their heart is large enough to puncture.

Newborn Calf Serum is sourced similarly; calves who are 20 days old or younger have their heart punctured and are bled to death.

These products are used as a media base and growth supplement in many different types of research.

In the news

Mycoplasma Bovis: "Researchers will measure how M. Bovis impacts infected animals and herds, including physical signs, effects on milk yield and quality, weight gain in cattle, and the duration of these effects." Read more.

Cow shock collars: "Animals wear GPS-enabled collars that identify their location relative to invisible fence lines created on a digital farm map. The animals are trained to be guided by audio prompts (beeps) from the collars when required. As an animal gets close to a virtual fence, a series of beeps alerts them to the fence boundary. If they cross the fence line, they receive a "disincentive", a mild electric shock, and are guided back inside the line." Read more.

Bobby calves: Bobby calves (male calves of dairy cows) are normally unwanted by the dairy industry. Researchers are cross-breeding dairy cows with beef breeds so that bobby calves can be killed and eaten after a year, rather than being killed as "excess" after 4 days. Read more

Climate change: AgResearch scientists have been given $10 million to develop cattle better adapted to warmer temperatures and to lower methane emissions. Read more.

Places that use cattle for science in NZ include universities such as Lincoln University (who have their own research dairy farm) and Massey University (they also have their own dairy farms), private companies such as Abacus Bio Limited and Cognosco, crown institutes such as AgResearch, industry bodies such as Dairy NZ and by other organisations and individuals.

Cattle used for science in NZ are sourced from commercial establishments, farms, public sources, breeding units and other sources.

Discover real-life examples of how cattle have been used in NZ below!
References:

Measuring thickness of blood vessel walls

Colony cats were anaesthetised, and the blood vessels under their tongue were measured with a special hand-held camera.

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Collecting faeces for lab tests

Colony cats were fed different diets for three weeks before their faeces was collected for analyses.

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Surveying caregivers on their cat feeding

New Zealand cat caregivers filled in an online survey about their household demographics and what/how they feed their cats.

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Testing new toxin in Hawke’s Bay (again)

Toxic bait traps were placed on a property in Hawke’s Bay. Cat population changes were monitored with stationary cameras.

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Assessing stress reaction to anaesthesia in cats

Cats were put through several anaesthetic infusions with six-day breaks in between. Regular saliva samples were taken 24 hours before and after, and urine was collected through a wire mesh tray.

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Trialling ready-made toxic bait

Toxic bait stations are set up in a regular pattern in an area and left for two weeks. Trial cameras and tracking tunnels monitor the effect on the population.

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Studying medical data of cat and dog CT-imaging

Medical data from cats and dogs were gathered, and animals that had been euthanised for other reasons were examined.

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Testing if a human diabetes drug might also work in cats

Research cats were placed in individual cages four times (one week each time) and injected with either a diabetes drug or a control solution. Several blood and urine samples were taken.

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Testing a cat food supplement for tooth health

Colony cats were anaesthetised, and all plaque was removed from their teeth. Four weeks later, new plaque build-up was measured.

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Sampling cats for feline immunodeficiency virus (FIV)

Buccal swabs (inside the cheek) were collected from almost 200 cats at 15 veterinary clinics.

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Testing food preferences of cats

Cats were fasted for two hours in the mornings and then presented with different foods (lamb and beef parts) to measure their consumption.

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Monitoring wild cats for a year

Wild cats are trapped and fitted with GPS collars. After one year, they are recaptured and killed.

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Trialling a lighter rifle to kill trapped wild cats

Captured wild cats were shot in the head using an air rifle and were assessed to confirm death by recording the time to loss of heartbeat.

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Testing a predictive marker for cancer survival in cats

Veterinary samples of cats with this form of cancer were analysed and compared with their remaining survival since diagnosis.

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Monitoring outdoor cat behaviour

Privately owned cats with outdoor access were fitted with camera and GPS collars for up to three days.

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Testing a diagnostic for feline coronavirus

Cats with specific symptoms were used to take blood, tissue, and fluid samples. Some blood samples were taken from control cats.

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Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

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Testing a fertility treatment

Cows with fertility problems were treated with hormones for ten days or left untreated. All were then artificially inseminated.

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Testing a supplement for more calcium intake

Pregnant cows were fed with or without a specific feed additive. After birth, all were fed the same diet. Blood samples were taken in the weeks around birth.

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Checking endometritis rates in dairy herds

Some cows in several dairy herds were selected, and their vaginal discharge was measured and sampled. They were then impregnated as per standard agricultural practice.

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Comparing weight gain with different diets

Newborn calves were raised on various milk, pasture, and pellets combinations. They were slaughtered at two years old, and their “quality” was measured.

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Testing pain meds for disbudding

The horn buds of young calves who were slightly sedated were burned off with a hot iron. Half of them received pain meds beforehand, and blood samples were taken before and after. After 24 hours, the second group received pain meds, too.

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Studying Ikeda infection and treatment

Regular blood samples were taken from cows on three different farms. Only some were treated against the parasite. Milk production and fertility were recorded.

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Studying diarrhea infection

New mother cows had blood samples taken. If the sample was negative for a diarrhoea virus, they were sampled again after a while.

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Studying genes for body size

Udders of dairy cows were slightly cut with a scalpel, and a tissue sample was taken with a biopsy needle.

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Testing toxicity of a potential new fertiliser

Pigs were fed toxic bait and monitored until they died.

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Studying stress around birth

Blood samples were taken from cows with a high or low risk of health concerns after birth.

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Studying genetics of a missing tail

Cloned foetuses were implanted into female cattle to research taillessness. Some of them were killed during pregnancy to examine the foetuses. One tailless animal was killed at age 4, and one of the cloned calves died after birth.

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Studying Ikeda (parasite) infection

Blood samples were taken from dairy cows and their calves directly after birth before separating them. After four months, the calves were sampled again.

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Studying Osteoporosis in cows

Young female cattle who had given birth for the first time were sent to slaughter. Half of them had broken bones for between 2 and 10 days. Blood samples were taken before slaughter, and bones were collected after.

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Testing a tuberculosis vaccine

Male calves were infected with bacteria. Two groups were vaccinated before or after the infection, and the third group was left untreated. All were killed and dissected 13 weeks later.

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Testing feeding plans for better immunity after calving

Pregnant cows were fed either a bit too much or a bit too little. Blood samples were taken before, at, and after calving. Researchers also took liver samples with a 20-cm biopsy needle and vaginal samples with a small brush and a scoop at these dates, except for the date of birth.

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Testing if blackcurrant extract is toxic for dogs

Dogs are given blackcurrant pills for several days. The number of pills increases over time up to 60 tablets. Their health is monitored.

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Practising first aid on working dogs

The 2-day course involved training students with mannequins, placing an IV catheter in the handler's dogs (dogs were lightly sedated), a live demo and practical exercises on anaesthetised sheep that would killed afterwards.

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Testing intermittent fasting

Dogs will be fed three different ways for one week each. A high carb diet twice a day, a high carb diet every two days, and a high fat, low carb diet every two days. Each dog will have 12 blood samples taken throughout the study.

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Testing the fitness level of police dogs

Police dogs are fitted with a catheter for a whole week and get infused with a marker solution. They are fitted with an activity measuring collar and regularly have blood sampled.

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Testing how sensitive some dog breeds are to pain

Dogs were tested for their pain threshold by having a disk the size of a coin placed onto one of their forelegs. This disc could be heated up remotely. Several tests with 10-minute breaks in-between were performed, where the disk temperature was raised until the dog showed signs of pain. Almost half the dogs showed burn marks after testing.

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Testing what dogs prefer to eat

Dogs are fed three different diets (either high fat, high carb, or high protein) over 28 days once a day. The dogs are offered each of the three diets at once and in high quantities. Regular stool samples are taken. Blood samples are taken from dogs that have been fasted (18 hours with no food).

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Studying how long morphine affects dogs

Dogs scheduled to have ovaries and uterus removed at a teaching clinic are used. Premedication, including morphine, is given 45min before the surgery. Dogs are fasted for 12 hours and water is withheld for about 1 hour before surgery. Blood samples are taken regularly for 4 hours.

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Studying the influence of diet on working farm dogs

Dogs working on farms are fed either a premium diet or a standard "home-kill plus tux" diet. All dogs have a collar to measure activity. Body weight, condition, and blood samples are recorded regularly for a year.

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Testing a new biomarker

For regular blood samples over nine weeks, dogs are fasted overnight at the lab and returned to their owners the next day until the following sampling.

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Studying if farm dogs are overworked

A glucose sensor is stuck between the dog's shoulder blades and sutured in place before a bandage is stapled over it. After being fasted, each dog is studied on glucose levels and activity for two days.

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Testing different methods for skin sampling

Samples from the skin of dogs are taken in different ways: plucking hair with the roots, sellotape strips pressed down and ripped off several times, acetone-soaked cotton buds and solvent washes.

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Testing nausea in dogs with different anaesthesia

Dogs who are about to have surgery are given different combinations of anti-nausea drugs to test the effects.

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Testing a breathing mask on cats and dogs

Cats and dogs were held down tightly and fitted with face masks. Their breathing was measured for a while.

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Learning when anaesthesia is lethal

The anaesthesia of pound dogs was gradually increased to dangerous levels. Students also practised taking blood samples, placing catheters and giving blood transfusions to the dogs, all while a teacher supervised.

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Testing a gene therapy for Mucopolysaccharidosis

Newborn puppies are genotyped and divided into treatment groups. Some are left untreated. Some are injected with potential medication. The injection is into the neck vein or into the liver vein. For that, puppies are anaesthetised, have their belly cut open and the drug injected into the liver vein. All puppies are killed after regular blood and one spinal fluid sample.

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Refining treatment for a (human) genetic disorder

Puppies with the genetic disorder MPS IIIA were treated with enzymes injected directly into the spinal fluid near the brain. Treatment was done until 22 -24 weeks old and varied in dose and frequency. In the end, the puppies were killed for dissection.

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Studying fish behaviour in groups of multiple species

Mixed-species groups of fish (partly caught in the wild) were placed in a tank and fasted for 24 hours. Food was given and an artificial predator was used to study behaviour.

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Studying food chains near CO2 vents

Fish and snails were observed and counted near CO2 vents and at control sites. Fish were also caught to examine their stomach content.

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Studying fish behaviour in single-species groups

Young fish were caught in the wild and split into groups of 15, 75, and 150 animals. After being fasted for 24 hours, food was given and an artificial predator was used to study behaviour.

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Testing the side-bias of fish (if they prefer to swim left or right)

Wild-caught fish were kept for 1.5 years before each fish was placed on a runway to observe their behaviour. Afterwards, fish were observed for schooling movements and some were killed to dissect their brains.

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Studying effects of Climate Change on farming in damselfish

Fish were observed for their algae farming behaviour near CO2 vents and at control sites (Bay of Plenty). Small areas were covered to keep the fish away for a month and compare algae growths measured to compare.

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Trying to estimate habitat quality from body condition

Snappers were hatched from eggs and raised on commercial food. They were kept in 800-litre flow-through tanks containing 170 to 260 fish each. At 80 days, they were fasted killed.

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Trying different techniques for tagging fish

Fish were bait-trapped and treated for parasites. They were used to test different tagging methods. In the second part of the experiment, fish were caught with two different methods, after which injuries and survival over 12 days were monitored.

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Studying fish near volcanic vents to learn about Climate Change

Fish near volcanic CO2 vents and at control sites were observed and counted. The reaction to baited underwater cameras and predator threats was filmed. Aquarium experiments were conducted with caught fish of different species.

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Verifying “fish-friendly” flood pumps

Eels were caught, measured and tagged with transponders into the gut skin. They were later re-captured, observed for wounds and fungus and killed to examine internal damage.

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Testing the temperature tolerance of Antarctic fish

Wild-caught fish were kept individually for months in tanks. During temperature experiments, fish of each group were tested for their breathing ability in small tubes before all fish were killed.

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Slowly poisoning fish

Snappers were fasted for three days and then fed with toxic fish. Several died during feeding, and the rest were killed at the end.

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Studying population changes in reef fish

Over 1,000 fish were caught by spearing at three NZ locations.

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Testing the hearing of fish

Fish were anaesthetised and strapped to a plastic slide near an underwater speaker. Electrodes were placed in their head and gills to measure brain activity. For medical imaging, fish were restrained in a plastic tube with a sponge to keep them wet.

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Developing a model for thermal stress in humans

Guinea pig pups were lightly anaesthetised, connected to devices measuring heart activity and breathing, and wrapped in a temperature-controlling blanket. Their body temperature was either forcefully raised or dropped.

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Testing how too much fructose is bad during pregnancy

Female guinea pigs were mated; some were fed additional sugary water until birth. The pups were used for several glucose tolerance tests and X-rays. All pups were killed in the end.

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Testing a seizure medicine for preterm babies

Pregnant guinea pigs were induced to give birth early, to test medication on their pups.

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Testing the effects of sedatives

Young guinea pigs were treated with different sedatives. Their heart rate and blood pressure were measured before and during each treatment.

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Testing an refined way of anaesthesia in guinea pigs

Guinea pigs were made to inhale anaesthetic gases. Different probes were inserted and attached to the animals to measure responses.

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Studying the effect of fructose during pregnancy

Guinea pigs were fed either normally or supplemented with fruit sugar before and during pregnancy until birth. Mothers and pups were tested for glucose tolerance.

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Studying the effects of meth

Guinea pigs were injected with sedatives, caffeine, and later meth. Under anaesthesia, their livers were cut out before they were killed.

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Studying preterm birth effects on the brain

Pregnant guinea pigs were grouped to give birth normally or be induced early. The pups were put through behavioural tests and then killed for dissection.

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Studying trauma and treatment of cochlear implants

After destroying their hearing with noise, guinea pigs were fitted with cochlear implants. Treatment success was tested before they were killed.

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Testing the measurement of pupil reflexes in Alzheimer’s research

Guinea pigs were repeatedly flashed in the eyes with a phone light to record the pupil responses.

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Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

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Investigating mechanisms slowing down the heart rate

Young guinea pigs were injected with blood thinner before being anaesthetised and dissected.

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Testing a device to assess hearing

Young guinea pigs were anaesthetised, electrodes placed under their skin, and their brain's response to sound was measured. All guinea pigs had one ear damaged, some both ears, before all were killed.

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Studying changes in the inner ear due to inflammation

Guinea pigs were injected into the ear with bacteria. Medical scans were done after injecting chemicals, and most were killed for dissection.

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Studying the effects of medication on memory

Guinea pigs were force-fed different drugs and later tested in a water maze before some were killed. Another group was exposed to carbon dioxide and decapitated.

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Studying how anaesthetics affect intestine movement

Guinea pigs and rats were anaesthetised, then dissected, and then killed, in that order.

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Testing a UV treatment for bacterial eye infection

Pigs’ eyes were acquired for testing a new treatment, followed by tests on live mice, most of whom were killed.

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Studying methane emission and meat quality

Sheep were bred for high and low methane emissions. Almost 2,000 were put through emission measurements. Over 17,000 were slaughtered.

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Testing if anaesthesia affects the sleep–wake cycle

Mice were kept on a 12-hour light/dark cycle and then switched to total darkness. They were anaesthetised twice to see the effect on their activity cycles, and all were killed in the end.

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Testing the influences on growth

Transgenic and "normal" mice were kept in small groups and killed at different ages. Fat and muscle tissue were dissected, and the hearts were taken.

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Testing a new way to kill lab mice

Mice were fed cream cheese containing different amounts of a sedative. Behaviour was recorded during the sedation period and while gassing them with CO2.

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Testing a possible cause for cataracts

Transgenic and "normal" mice were used to study the development of cataracts. They were anaesthetised, images of their eyes were taken, and then they were (likely all) killed.

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Studying chronic stress

Mice were handled daily, had vaginal smears, and some were subject to the notorious Forced Swim Test. Half of them were additionally stressed daily in various ways to see the difference it makes.

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Trialling cancer drugs in mice after similar drug failed in humans

Mice were force-fed daily with two new drugs in different dosages. Others were force-fed a control solution, and some were left untreated. In the end, the animals were killed with CO2 and dissected.

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Testing if exercise influences treatment success with cancer

Mice were injected with cancer cells. When tumours reached an “ethical” limit, they were injected with a labelling agent, anaesthetised and killed to be dissected. This was repeated, while some mice received cancer treatment.

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Testing if exercise influences muscle mass with cancer

Mice were injected with cancer cells, and some received immunotherapy once the tumour reached a specific size. When tumours reached an “ethical” limit, they were killed. Cancer-free control mice were killed simultaneously.

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Studying the interaction of hormones and stress

Transgenic mice had their brains injected, some had their ovaries removed, and some were restrained for repeated blood samples. In the end, all mice were killed.

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Studying movement processing in the brain

Transgenic mice were put through behavioural tests while half of them had a part of their brain-damaged. Some mice had a window put into their skull to take recordings of their brains while awake. They had limited access to water and were forced into a device that stopped them from moving their head. In the end, all were killed.

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Testing seizure activity in transgenic mice

Mice with specific genetic limitations were bred. Some were killed for dissection, and others were injected with a gene activation drug before they were killed.

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Testing a seizure treatment

Genetically modified mice had wires and a cannula implanted in their brains, and were injected to cause seizures. The next day, their genetic mutation was activated. The test was repeated before they were all killed.

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Observing cancer growth with/without treatment

Mice were injected with human breast cancer cells. The growth was monitored and sampled (biopsy). Some were operated on to remove their ovaries and some were treated with drugs before all were killed.

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Testing how hormones influence activity while pregnant

Transgenic and “normal” mice were used to test the influence of pregnancy and hormones on activity and anxiety. They were kept in single cages with running wheels and subjected to behavioural tests. The transgenic mice were killed in the end.

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Studying the effect of certain lipids in formula on brain development

Piglets were kept individually and fed formula with different supplementation. After 18 days, they were killed.

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Harvesting bladders to study contraction patterns

The bladders of six pigs were surgically removed under anaesthesia before the pigs were killed.

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Testing toxic bait

Pigs were fed toxic bait and monitored until they died.

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Testing the effect of a shot to the head

Pigs were anaesthetised and shot in the back of the head from different distances. Effects were recorded and analysed.

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Training students in surgical procedures

Pigs and sheep were used for training future surgeons.

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Teaching students surgical techniques

Sheep and pigs were used and killed in teaching students.

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Testing the viability of xenotransplantation using islet capsules

Newborn piglets were killed for their pancreas. Encapsulated pancreas cells were then implanted into young mice, who were killed later to retrieve the capsules.

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Testing measurement of specific proteins

Pigs were surgically fitted with an outside access to their intestine and kept individually for eight weeks. Digestive matter was collected over ten hours on one day, while the pigs had no access to food or water.

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Studying the spread of bovine tuberculosis in pigs

Pigs were bought, and wild pigs were captured and distributed through two studies over almost two years. Pigs were killed regularly to dissect them for tuberculosis signs.

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Studying wound healing treatments

Pigs were anaesthetised and wounded in 20 places on their backs. The wounds were treated differently and sampled over a month before the pigs were killed.

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Developing a model for varicose veins

Blood vessels in pigs' legs were surgically altered, and some pigs were fitted with devices to measure blood pressure. After weeks of regular examinations, all were killed.

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Testing how long you have to wait to shoot and eat poisoned wild pigs

Piglets were fed different amounts of rat poison for longer or shorter periods before they were all killed.

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Testing how many cancer cells spill out during colon surgery

Pigs were anaesthetised and injected with radioactive cancer cells. Different colon surgeries were performed.

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Comparing effects of anaesthetics on breathing and heart rate

Guinea pigs, rabbits and rats were anaesthetised, and a tube was put into their windpipe through the neck. They were made to breathe anaesthetic gas.

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Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

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Using sheep to try and model how well humans will heal after dental surgery

Sheep were anaesthetised, three teeth were pulled, and the sockets were treated differently. For months, regular samples were taken from the healing wounds before all sheep were killed.

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Preclinical testing of a gene therapy for Batten disease

Sheep with and without a specific gene mutation were checked and scanned regularly for nine months. Affected sheep received gene therapy at different ages. Treated sheep were killed.

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Testing if blocking a cell signal can prevent foetal brain injury

Pregnant sheep were anaesthetised, and the foetuses fitted with electrodes. The umbilical cord was blocked for most of them, and half were treated with a test drug. Mothers and unborn lambs were killed three weeks later.

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Testing the combination of drugs for congestive heart failure treatment

Sheep were anaesthetised and subjected to surgery. Electrodes were used to pace their hearts faster while testing the effect of different drugs.

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Testing the best way to deliver gene therapy drugs

Sheep were anaesthetised. Their heads were drilled into, and their brains injected with test drugs. They were killed after three weeks.

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Testing the potency of pneumonia vaccines for sheep

Lambs were vaccinated twice, and regular blood samples were taken for 34 weeks.

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Testing the effects and wash-out of painkillers

Lambs were treated with different painkillers or not at all before tail docking and castration. Their behaviour was monitored.

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Developing “hyperimmune” milk

Sheep were injected with Covid-19 vaccines, and regular blood samples were taken. Some were mated and gave birth to sample their milk, too.

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Studying the genetics of Batten disease on chimeric lambs

Sheep foetuses were removed. After swapping cells between them, they were inserted into other ewes. Lambs born were subjected to X-rays and, at one to three years old, were bled out for dissection.

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Testing pacemaker adjustments

After causing them heart failure, sheep were surgically fitted with pacemakers and measurement devices. Those who survived the procedures were killed after six months.

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Studying methane emission and meat quality

Sheep were bred for high and low methane emissions. Almost 2,000 were put through emission measurements. Over 17,000 were slaughtered.

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Studying the effect of chemicals in normal and high blood pressure

Sheep were surgically fitted with a clip around an artery, or they served as control. Measuring devices were added before injecting different chemicals into the hearts of the conscious sheep.

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Comparing muscle repair success with and without weeks of delay

Ewes were anaesthetised, and one side of a pelvis muscle was detached. After several weeks, the muscle was repaired. Gait was evaluated before all were killed.

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Comparing different designs of dental implants

Sheep were anaesthetised. One leg bone was exposed and fitted with several implants. After 12 weeks, all were killed.

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Trying to model human brain injuries

To study changes in different areas of the brain after brain injuries. Sheep were used to study the effects of traumatic brain injuries in humans.

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Testing efficiency of strip-sowing 1080 bait

The toxin ‘1080’ was distributed as complete coverage and in a strip pattern. Effects on the wild rabbit numbers were evaluated.

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Testing new formulations of eye medication

The eyes of albino rabbits were treated with different medications. At regular intervals, several of them were killed.

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Taking blood samples over several days

Two New Zealand white rabbits were anaesthetised and restrained. Catheters were put into their ear veins to inject a solution and take regular blood samples.

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Harvesting rabbit caecum for more lab tests

Domestic dwarf rabbits were anaesthetised, their caecum was cut out, and then they were killed.

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Using rabbits as a model for human atherosclerosis

NZ White rabbits were fed pellets with or without added cholesterol for 10 weeks. They were killed with anaesthetic and taking blood from their heart until it stopped.

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Testing new drug formulations

NZ White rabbits were given a new drug formulation or ketamine. Righting reflex, paw withdrawal, and blood parameters were checked every minute.

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Infecting rabbits with a virus to have more samples of it

Samples of dead wild rabbits were taken to collect virus material. The virus was then used to infect rabbits and analyse their tissue.

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Injuring the sinus tract to test medication

NZ White rabbits were anaesthetised, and the sinus tracts in their nose were purposely injured to the bone. Two weeks after treatment, they were killed.

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Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

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Testing new drug formulations

Rats and rabbits were injected with a new anaesthetic, pinching their paw repeatedly to measure reflexes. Rats were giving the medication until they died.

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Testing the behaviour of a drug in rabbits’ blood

NZ White rabbits were infused with different medications, and blood samples were taken regularly for 24 hours.

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Testing a new drug delivery formulation

NZ White rabbits were injected with a radioactive solution, wrapped tightly, and recorded this way for 90min.

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Placing metal into rabbits’ jaws

NZ White rabbits were anaesthetised, and metal spheres were placed into their jaws. X-rays were taken to measure bone growth.

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Using rabbits as glaucoma surgery model

The eyes of NZ White rabbits were surgically opened and treated with different solutions. At intervals, some were killed to analyse the eye tissue.

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Monitoring vital signs of rabbits during intercourse

NZ White rabbits were anaesthetised and implanted with devices to measure vital signs. They were then monitored during intercourse.

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Harvesting rabbit caecum for lab tests

Domesticated rabbits were anaesthetised. Part of their digestive tract was removed, and then they were killed.

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