Fish

Learn about the many surprising ways that fish are used for science in NZ.

Fish were the single most used species for science in 2020.1 Most were used in basic biological research (the study of living things and their processes) and were also used in animal husbandry research, species conservation, and more.

Why so many fish are used: Most fish have a very short reproductive cycle, meaning they can be bred quickly, they also don't generally cost much to breed or house, making them desirable test subjects in science.

Zebrafish are regularly used as animal models for human development. A single pair of zebrafish can produce 100 to 300 embryos in one week. Zebrafish embryos are transparent and have their whole “body plan” laid down only 2 days after fertilisation. The similarity between human and zebrafish genomes is often cited as a reason to use them in models.2 

Snapper3, eels4 and other fish that are eaten5 are also regularly used in science because of their importance to the commercial fishery. This industry will always be looking for ways to maximise its profits.4

Many fish living in the wild are studied as a way to research climate change.

Fish in NZ have been used for:

1. Research into optimising the growth and use of fish for human consumption. This includes research into optimal feeding, genes responsible for body size and growth speed.

Other examples include:

  • Testing environmental influences and impacts (i.e. how salmon farms affect surrounding ecosystems).
  • Researching how toxins accumulate in fish organs (i.e. algae toxins, mercury).
  • Finding treatments/vaccines for illnesses and injuries from aquaculture.
  • Manipulating the life cycle of fish to try and maximise reproduction.

2. Teaching purposes in schools and universities, including observational activities and dissections.

3. Medical research (i.e., they are used to try and model humans).

Examples include:

  • Fish larvae have been used to try and model human immunity.
  • Fish embryos have been used to try and study human foetal development.
  • Genetically modified fish have been used to try and study adipostasis and glucose metabolism.

4. Basic research into fish biology, including research into how sharks sleep, how hearing develops in fish, microbes inside fish stomachs and the spread of viruses in wild fish.

5. Research into the effects of climate change, including research into marine food webs, biodiversity changes, species behaviour and interactions and predator abundance.

Other examples include research into:

  • Measuring the genetic reactions to stress.
  • The effects of herbicides on fish behaviour
  • How well Arctic fish do at higher temperatures.

6. Species conservation, including research into killing unwanted species (i.e., koi carb, catfish, rudd, and goldfish).

Other examples include research into:

  • The efficiency of one-way barriers on lake outflow.
  • Fish-friendly flood pumps (i.e. for eels).
  • Finding out where wild fish breed the most (to see which areas are worth protecting).
  • Optimising catching/tagging methods for re-capture projects.

7. Ecotoxicity testing (i.e., in tests that measure how biological, chemical or physical stressors affect ecosystems).

Places that use fish for science in NZ include universities, crown research institutes, polytechnics, commercial organisations and others.

The University of Otago for example has its own Zebrafish Facility. The MPI naturally has a research interest in fisheries and ecosystems. As a crown research institute, NIWA’s research in the fields of aquaculture, fisheries, and the Antarctic is funded by the government. Cawthron Aquaculture Park is home to a dedicated Finfish Research Centre (FRC), which opened in 2018 with funding support from the Ministry of Business, Innovation and Employment (MBIE).

Fish used for science in NZ are sourced from breeding units, fish farms, commercial sources, and public sources, are born during projects or are captured in the wild.

Discover real-life examples of how fish have been used in NZ below!

Measuring thickness of blood vessel walls

Colony cats were anaesthetised, and the blood vessels under their tongue were measured with a special hand-held camera.

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Collecting faeces for lab tests

Colony cats were fed different diets for three weeks before their faeces was collected for analyses.

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Surveying caregivers on their cat feeding

New Zealand cat caregivers filled in an online survey about their household demographics and what/how they feed their cats.

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Testing new toxin in Hawke’s Bay (again)

Toxic bait traps were placed on a property in Hawke’s Bay. Cat population changes were monitored with stationary cameras.

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Assessing stress reaction to anaesthesia in cats

Cats were put through several anaesthetic infusions with six-day breaks in between. Regular saliva samples were taken 24 hours before and after, and urine was collected through a wire mesh tray.

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Trialling ready-made toxic bait

Toxic bait stations are set up in a regular pattern in an area and left for two weeks. Trial cameras and tracking tunnels monitor the effect on the population.

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Studying medical data of cat and dog CT-imaging

Medical data from cats and dogs were gathered, and animals that had been euthanised for other reasons were examined.

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Testing if a human diabetes drug might also work in cats

Research cats were placed in individual cages four times (one week each time) and injected with either a diabetes drug or a control solution. Several blood and urine samples were taken.

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Testing a cat food supplement for tooth health

Colony cats were anaesthetised, and all plaque was removed from their teeth. Four weeks later, new plaque build-up was measured.

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Sampling cats for feline immunodeficiency virus (FIV)

Buccal swabs (inside the cheek) were collected from almost 200 cats at 15 veterinary clinics.

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Testing food preferences of cats

Cats were fasted for two hours in the mornings and then presented with different foods (lamb and beef parts) to measure their consumption.

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Monitoring wild cats for a year

Wild cats are trapped and fitted with GPS collars. After one year, they are recaptured and killed.

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Trialling a lighter rifle to kill trapped wild cats

Captured wild cats were shot in the head using an air rifle and were assessed to confirm death by recording the time to loss of heartbeat.

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Testing a predictive marker for cancer survival in cats

Veterinary samples of cats with this form of cancer were analysed and compared with their remaining survival since diagnosis.

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Monitoring outdoor cat behaviour

Privately owned cats with outdoor access were fitted with camera and GPS collars for up to three days.

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Testing a diagnostic for feline coronavirus

Cats with specific symptoms were used to take blood, tissue, and fluid samples. Some blood samples were taken from control cats.

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Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

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Testing a fertility treatment

Cows with fertility problems were treated with hormones for ten days or left untreated. All were then artificially inseminated.

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Testing a supplement for more calcium intake

Pregnant cows were fed with or without a specific feed additive. After birth, all were fed the same diet. Blood samples were taken in the weeks around birth.

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Checking endometritis rates in dairy herds

Some cows in several dairy herds were selected, and their vaginal discharge was measured and sampled. They were then impregnated as per standard agricultural practice.

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Comparing weight gain with different diets

Newborn calves were raised on various milk, pasture, and pellets combinations. They were slaughtered at two years old, and their “quality” was measured.

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Testing pain meds for disbudding

The horn buds of young calves who were slightly sedated were burned off with a hot iron. Half of them received pain meds beforehand, and blood samples were taken before and after. After 24 hours, the second group received pain meds, too.

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Studying Ikeda infection and treatment

Regular blood samples were taken from cows on three different farms. Only some were treated against the parasite. Milk production and fertility were recorded.

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Studying diarrhea infection

New mother cows had blood samples taken. If the sample was negative for a diarrhoea virus, they were sampled again after a while.

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Studying genes for body size

Udders of dairy cows were slightly cut with a scalpel, and a tissue sample was taken with a biopsy needle.

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Testing toxicity of a potential new fertiliser

Pigs were fed toxic bait and monitored until they died.

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Studying stress around birth

Blood samples were taken from cows with a high or low risk of health concerns after birth.

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Studying genetics of a missing tail

Cloned foetuses were implanted into female cattle to research taillessness. Some of them were killed during pregnancy to examine the foetuses. One tailless animal was killed at age 4, and one of the cloned calves died after birth.

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Studying Ikeda (parasite) infection

Blood samples were taken from dairy cows and their calves directly after birth before separating them. After four months, the calves were sampled again.

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Studying Osteoporosis in cows

Young female cattle who had given birth for the first time were sent to slaughter. Half of them had broken bones for between 2 and 10 days. Blood samples were taken before slaughter, and bones were collected after.

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Testing a tuberculosis vaccine

Male calves were infected with bacteria. Two groups were vaccinated before or after the infection, and the third group was left untreated. All were killed and dissected 13 weeks later.

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Testing feeding plans for better immunity after calving

Pregnant cows were fed either a bit too much or a bit too little. Blood samples were taken before, at, and after calving. Researchers also took liver samples with a 20-cm biopsy needle and vaginal samples with a small brush and a scoop at these dates, except for the date of birth.

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Testing if blackcurrant extract is toxic for dogs

Dogs are given blackcurrant pills for several days. The number of pills increases over time up to 60 tablets. Their health is monitored.

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Practising first aid on working dogs

The 2-day course involved training students with mannequins, placing an IV catheter in the handler's dogs (dogs were lightly sedated), a live demo and practical exercises on anaesthetised sheep that would killed afterwards.

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Testing intermittent fasting

Dogs will be fed three different ways for one week each. A high carb diet twice a day, a high carb diet every two days, and a high fat, low carb diet every two days. Each dog will have 12 blood samples taken throughout the study.

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Testing the fitness level of police dogs

Police dogs are fitted with a catheter for a whole week and get infused with a marker solution. They are fitted with an activity measuring collar and regularly have blood sampled.

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Testing how sensitive some dog breeds are to pain

Dogs were tested for their pain threshold by having a disk the size of a coin placed onto one of their forelegs. This disc could be heated up remotely. Several tests with 10-minute breaks in-between were performed, where the disk temperature was raised until the dog showed signs of pain. Almost half the dogs showed burn marks after testing.

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Testing what dogs prefer to eat

Dogs are fed three different diets (either high fat, high carb, or high protein) over 28 days once a day. The dogs are offered each of the three diets at once and in high quantities. Regular stool samples are taken. Blood samples are taken from dogs that have been fasted (18 hours with no food).

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Studying how long morphine affects dogs

Dogs scheduled to have ovaries and uterus removed at a teaching clinic are used. Premedication, including morphine, is given 45min before the surgery. Dogs are fasted for 12 hours and water is withheld for about 1 hour before surgery. Blood samples are taken regularly for 4 hours.

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Studying the influence of diet on working farm dogs

Dogs working on farms are fed either a premium diet or a standard "home-kill plus tux" diet. All dogs have a collar to measure activity. Body weight, condition, and blood samples are recorded regularly for a year.

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Testing a new biomarker

For regular blood samples over nine weeks, dogs are fasted overnight at the lab and returned to their owners the next day until the following sampling.

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Studying if farm dogs are overworked

A glucose sensor is stuck between the dog's shoulder blades and sutured in place before a bandage is stapled over it. After being fasted, each dog is studied on glucose levels and activity for two days.

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Testing different methods for skin sampling

Samples from the skin of dogs are taken in different ways: plucking hair with the roots, sellotape strips pressed down and ripped off several times, acetone-soaked cotton buds and solvent washes.

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Testing nausea in dogs with different anaesthesia

Dogs who are about to have surgery are given different combinations of anti-nausea drugs to test the effects.

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Testing a breathing mask on cats and dogs

Cats and dogs were held down tightly and fitted with face masks. Their breathing was measured for a while.

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Learning when anaesthesia is lethal

The anaesthesia of pound dogs was gradually increased to dangerous levels. Students also practised taking blood samples, placing catheters and giving blood transfusions to the dogs, all while a teacher supervised.

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Testing a gene therapy for Mucopolysaccharidosis

Newborn puppies are genotyped and divided into treatment groups. Some are left untreated. Some are injected with potential medication. The injection is into the neck vein or into the liver vein. For that, puppies are anaesthetised, have their belly cut open and the drug injected into the liver vein. All puppies are killed after regular blood and one spinal fluid sample.

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Refining treatment for a (human) genetic disorder

Puppies with the genetic disorder MPS IIIA were treated with enzymes injected directly into the spinal fluid near the brain. Treatment was done until 22 -24 weeks old and varied in dose and frequency. In the end, the puppies were killed for dissection.

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Studying fish behaviour in groups of multiple species

Mixed-species groups of fish (partly caught in the wild) were placed in a tank and fasted for 24 hours. Food was given and an artificial predator was used to study behaviour.

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Studying food chains near CO2 vents

Fish and snails were observed and counted near CO2 vents and at control sites. Fish were also caught to examine their stomach content.

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Studying fish behaviour in single-species groups

Young fish were caught in the wild and split into groups of 15, 75, and 150 animals. After being fasted for 24 hours, food was given and an artificial predator was used to study behaviour.

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Testing the side-bias of fish (if they prefer to swim left or right)

Wild-caught fish were kept for 1.5 years before each fish was placed on a runway to observe their behaviour. Afterwards, fish were observed for schooling movements and some were killed to dissect their brains.

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Studying effects of Climate Change on farming in damselfish

Fish were observed for their algae farming behaviour near CO2 vents and at control sites (Bay of Plenty). Small areas were covered to keep the fish away for a month and compare algae growths measured to compare.

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Trying to estimate habitat quality from body condition

Snappers were hatched from eggs and raised on commercial food. They were kept in 800-litre flow-through tanks containing 170 to 260 fish each. At 80 days, they were fasted killed.

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Trying different techniques for tagging fish

Fish were bait-trapped and treated for parasites. They were used to test different tagging methods. In the second part of the experiment, fish were caught with two different methods, after which injuries and survival over 12 days were monitored.

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Studying fish near volcanic vents to learn about Climate Change

Fish near volcanic CO2 vents and at control sites were observed and counted. The reaction to baited underwater cameras and predator threats was filmed. Aquarium experiments were conducted with caught fish of different species.

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Verifying “fish-friendly” flood pumps

Eels were caught, measured and tagged with transponders into the gut skin. They were later re-captured, observed for wounds and fungus and killed to examine internal damage.

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Testing the temperature tolerance of Antarctic fish

Wild-caught fish were kept individually for months in tanks. During temperature experiments, fish of each group were tested for their breathing ability in small tubes before all fish were killed.

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Slowly poisoning fish

Snappers were fasted for three days and then fed with toxic fish. Several died during feeding, and the rest were killed at the end.

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Studying population changes in reef fish

Over 1,000 fish were caught by spearing at three NZ locations.

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Testing the hearing of fish

Fish were anaesthetised and strapped to a plastic slide near an underwater speaker. Electrodes were placed in their head and gills to measure brain activity. For medical imaging, fish were restrained in a plastic tube with a sponge to keep them wet.

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Questioning vets on pain management

Veterinarians completed a questionnaire regarding pain and pain management in rabbits and guinea pigs.

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Testing nerve reactions to electric stimulation

Young guinea pigs were bled to death. Specific nerves were removed and experimented on.

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Studying short-sightedness

Guinea pigs had one eye covered for two weeks before increasing their eye pressure surgically and kill them.

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Measuring nerve reactions to gases

Guinea pigs were anaesthetised, and their windpipe and blood vessels were cannulated. They were exposed to different gases and cyanide while measuring breathing and nerve activity.

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Studying how anaesthesia affects breathing and heart

Guinea pigs were put in airtight chambers to test the effects of low oxygen. Some were surgically fitted with tubing so blood samples could be taken during the tests. In the end, all were killed.

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Studying compensation after inner ear destruction

Guinea pigs were anaesthetised, and their inner ear was destroyed with a drill. Videos were made for over two days of their balance recovery.

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Killing pregnant guinea pigs for tissue cultures

Pregnant guinea pigs were anaesthetised at specific time points of their pregnancy, including during labour, to then remove the uterus for tissue culture experiments.

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Testing how oxytocin injections cause contractions

Pregnant guinea pigs were surgically implanted with electrodes on or near the uterus. They were injected with oxytocin in specific doses and timeframes, and the effects were measured.

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Harvesting testicles for studies

Male guinea pigs were killed with CO2 to remove their testicles for experiments.

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Testing a new tuberculosis vaccine

A new tuberculosis vaccine was tested by injecting guinea pigs with the bacteria, either with or without prior vaccination. After several weeks, all were killed.

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Testing how heart calcium metabolism is different in species

Guinea pigs and rats were decapitated, and their hearts were quickly removed to study them.

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Testing influences on the rate of a dissected heart

Albino guinea pigs were anaesthetised and dissected before they were killed.

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Confirming the correlation of energy storage and stress in the inner ear fluid

Guinea pigs were anaesthetised and artificially ventilated. Ear fluid samples were taken through a hole in the skull, while exposing them to noise or lack of oxygen.

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Comparing natural and genetically altered tuberculosis strains

Guinea pigs were infected with tuberculosis strains after being injected with bacterial proteins beforehand. In the end, all guinea pigs were killed and dissected.

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Comparing effects of anaesthetics on breathing and heart rate

Guinea pigs, rabbits and rats were anaesthetised, and a tube was put into their windpipe through the neck. They were made to breathe anaesthetic gas.

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Testing motherly instinct towards foster pups

Mice of different “status” (never pregnant, pregnant, new mums) were made to rescue foster pups they didn’t know from several places. Transgenic mice lacking a prolactin brain receptor were tested for anxiety behaviour in the standard elevated-plus-maze.

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Testing new cancer vaccines

Mice were injected with cancer cells, followed by one of several potential vaccines. They were killed when tumours reached a certain size, or it became otherwise inhumane to keep them alive.

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Testing if pregnancy affects the healing of teeth

Pregnant and non-pregnant mice were taken. After the pregnant ones gave birth, all mice were anaesthetised. Some of their teeth were forcefully moved. Two weeks later, all were killed.

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Testing the effect of obesity during pregnancy

Pregnant mice were fed high-fat diets and had their babies removed via caesarean section. The foetuses were decapitated. Other newborn mice were separated to record their calls.

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Testing how motherly mice are

Transgenic mice were compared to “normal” mice on rescuing pups and how they care for their babies. They were mated, gave birth, and then put through behavioural tests involving newborn mice. After a few weeks, they were killed.

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Testing a medicine against drug addiction

Mice's tails were dunked in hot water. Rats were put through cycles of drug-seeking and withdrawal using self-injection of cocaine. Other rats were injected, and their behaviour was tested (with the notorious Forces Swim Test, among others).

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Teaching animal researchers

A range of animals is used to teach researchers handling and experimental methods.

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Testing the viability of xenotransplantation using islet capsules

Newborn piglets were killed for their pancreas. Encapsulated pancreas cells were then implanted into young mice, who were killed later to retrieve the capsules.

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Studying the digestion of kiwifruit

Pigs were surgically fitted with an outside access to their intestine. Faeces were collected through anal stimulation, and samples were taken from the intestine for six-hour periods.

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Testing feed supplements for their performance

Pigs were fed diets with different organic acids added. At a specific weight, they were slaughtered to collect samples.

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Comparing the digestion of egg white in different forms

Pigs were acclimated to eating egg whites of different textures. After being deprived of water for two hours, they were fed again and then killed in intervals over six hours.

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Testing ways of injecting nicotine

Pigs were anaesthetised and injected with nicotine through different methods. Blood samples were taken for two hours before the pigs were killed.

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Measuring brain response to tail-docking

Piglets were bought at one to fifteen days old and anaesthetised. Their tails were cut off while measuring brain activity, and then they were killed.

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Testing how cooking affects beef digestion

Pigs were fed ground beef for three days, either raw or cooked. They were then killed to cut out a part of their intestine.

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Trialling a method to measure intestine fermentation

Young pigs were fed a test diet for two weeks while confined in metabolic chambers. After that, they were killed with an anaesthetic injected into the heart.

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Testing how to gas piglets

Piglets were gassed plastic box to record their behaviour and vital signs.

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Testing the accuracy of heart activity measurements

Pigs were anaesthetised, their open chests were equipped with electrodes and closed again. After measurements, the hearts were stopped, images were taken, and the hearts were removed.

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Testing cholesterol absorption from baby formula

One-week-old piglets were kept in metabolic crates and fed baby formula for three weeks. They were then anaesthetised and killed to be dissected.

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Studying the digestion of protein through serial slaughter

Ninety young pigs were housed individually for 13 days; their diet contained kiwi fruit and beef. All were killed to be dissected.

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Studying the inner functions of the heart

Pigs were anaesthetised and their chests were cut open. Electrodes were inserted into their hearts so measurements could be taken before their hearts were removed.

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Testing the effect of pain killers during tail docking

Piglets were anaesthetised and their tails were removed using different methods. During these procedures, the heart and brain activity of the pigs were measured.

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Testing if pigs spread kauri tree sickness

A group of pigs was fed infected kauri roots for one day, and their faeces were collected for a week. Over 270 wild pigs were shot, and their stomach contents was sampled.

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Trialing xenotransplantation for diabetes

Four pigs were used to harvest cells for transplantation into humans.

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Studying sow and piglet behaviour in crates and pens

Sows and their newborn piglets were put in tightly confined crates or pens with slightly more room and their behaviour was observed.

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Comparing effects of anaesthetics on breathing and heart rate

Guinea pigs, rabbits and rats were anaesthetised, and a tube was put into their windpipe through the neck. They were made to breathe anaesthetic gas.

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Investigating how worms spread between lambs and calves

Lambs and calves were treated against parasites and then infected with worm eggs. Infection status was monitored. This was repeated several times before all sheep were killed.

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Using sheep to try and model how well humans will heal after dental surgery

Sheep were anaesthetised, three teeth were pulled, and the sockets were treated differently. For months, regular samples were taken from the healing wounds before all sheep were killed.

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Preclinical testing of a gene therapy for Batten disease

Sheep with and without a specific gene mutation were checked and scanned regularly for nine months. Affected sheep received gene therapy at different ages. Treated sheep were killed.

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Testing if blocking a cell signal can prevent foetal brain injury

Pregnant sheep were anaesthetised, and the foetuses fitted with electrodes. The umbilical cord was blocked for most of them, and half were treated with a test drug. Mothers and unborn lambs were killed three weeks later.

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Testing the combination of drugs for congestive heart failure treatment

Sheep were anaesthetised and subjected to surgery. Electrodes were used to pace their hearts faster while testing the effect of different drugs.

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Testing the best way to deliver gene therapy drugs

Sheep were anaesthetised. Their heads were drilled into, and their brains injected with test drugs. They were killed after three weeks.

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Testing the potency of pneumonia vaccines for sheep

Lambs were vaccinated twice, and regular blood samples were taken for 34 weeks.

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Testing the effects and wash-out of painkillers

Lambs were treated with different painkillers or not at all before tail docking and castration. Their behaviour was monitored.

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Developing “hyperimmune” milk

Sheep were injected with Covid-19 vaccines, and regular blood samples were taken. Some were mated and gave birth to sample their milk, too.

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Studying the genetics of Batten disease on chimeric lambs

Sheep foetuses were removed. After swapping cells between them, they were inserted into other ewes. Lambs born were subjected to X-rays and, at one to three years old, were bled out for dissection.

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Testing pacemaker adjustments

After causing them heart failure, sheep were surgically fitted with pacemakers and measurement devices. Those who survived the procedures were killed after six months.

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Studying methane emission and meat quality

Sheep were bred for high and low methane emissions. Almost 2,000 were put through emission measurements. Over 17,000 were slaughtered.

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Studying the effect of chemicals in normal and high blood pressure

Sheep were surgically fitted with a clip around an artery, or they served as control. Measuring devices were added before injecting different chemicals into the hearts of the conscious sheep.

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Comparing muscle repair success with and without weeks of delay

Ewes were anaesthetised, and one side of a pelvis muscle was detached. After several weeks, the muscle was repaired. Gait was evaluated before all were killed.

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Comparing different designs of dental implants

Sheep were anaesthetised. One leg bone was exposed and fitted with several implants. After 12 weeks, all were killed.

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Trying to model human brain injuries

To study changes in different areas of the brain after brain injuries. Sheep were used to study the effects of traumatic brain injuries in humans.

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Investigating intestine movements

Young pigs and NZ White rabbits were anaesthetised. A part of their intestine was pulled out far enough to record its movements and signalling.

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Harvesting rabbit and pig eyes for lab tests

The eyes of slaughtered rabbits and pigs killed for experiments were used to analyse the structure of the cornea.

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Causing sinusitis in rabbits as a model

NZ White rabbits were anaesthetised, and a sinus tract in their nose was blocked for four weeks to cause sinusitis. After another ten weeks with regular samples, they were killed.

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Testing a new vaccine

NZ White rabbits were injected with a new vaccine type several times before being killed.

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Harvesting eyes for lab tests

The eyes of pigs and rabbits killed for experiments were used to analyse the structure of the cornea.

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Testing the toxicity of some substances

Young NZ White rabbits were force-fed different doses of toxic substances. Blood samples were taken before and immediately after killing them at set time points (or to end their suffering).

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Using a new imaging technology

One NZ White rabbit and rats were killed, and their eyes were removed to use for the study.

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Measuring contractions in exposed rabbit uteruses

Pregnant rabbits were anaesthetised, and their uterus was exposed. Measurements were taken while contraction-inducing injections were given. Then they were all killed for dissection.

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Mapping wave patterns of the small intestine

NZ White rabbits were anaesthetised, their intestines were used for electrode mapping, and then they were killed.

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Studying presence of a virus in rabbits

Wild rabbits were shot, caught by dogs or trapped to test them for virus strains. The infectious solution was then fed to NZ White rabbits in a lab to kill them later.

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Harvesting rabbit colons for lab tests

NZ White rabbits were anaesthetised, a part of their intestine was cut out, and then they were killed.

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Harvesting rabbit bladders for lab tests

NZ White rabbits were anaesthetised, their bladder was cut out, and then they were killed.

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Testing an antimicrobial eye medication

NZ White rabbits were treated with Manuka honey solution in one eye and a control solution in the other eye for five days. Different values like tearing and irritation were measured.

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Using muscles of dead rabbits for imaging

Two NZ White rabbits were killed to use for detailed muscle imaging.

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Measuring jaw bone growth in young rabbits

Young rabbits were anaesthetised and had holes drilled into their jawbones to implant small pieces of metal. X-ray scans were made, and the rabbits were killed.

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Testing the welfare impact of pindone toxin

Three groups of young NZ White Rabbits received pindone-toxin pellets on different schedules. Any rabbit still alive after three weeks was killed.

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